SCHEMBL12112596

SCHEMBL12112596

Cc1cc(-c2ccccc2)nc2c1ccc1ccc(-c3ccc(-c4ccc5ccc6c(C)cc(-c7ccccc7)nc6c5n4)cc3)nc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.47
MAPT P10636 5/20 0.47
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
KDM4E B2RXH2 3/20 0.47
RAB9A P51151 2/20 0.47
POLB P06746 1/20 0.47
PKM P14618 1/20 0.47
ADORA1 P30542 4/20 0.43
ADORA2A P29274 3/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
HPGD P15428 1/20 0.42
PPARA Q07869 1/20 0.42
PARP1 P09874 1/20 0.41
AHR P35869 1/20 0.41
NPC1 O15118 1/20 0.40
HCRTR1 O43613 1/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19009618 1.00 ALDH1A1 (0.47) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL16678847 0.98 ALDH1A1 (0.49) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL23434425 0.94 MEN1 (0.46) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL23433975 0.94 MEN1 (0.46) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL23433974 0.94 MEN1 (0.47) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL23434430 0.94 MEN1 (0.47) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL23434296 0.94 MEN1 (0.46) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL23434427 0.94 MEN1 (0.47) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL23433976 0.94 MEN1 (0.47) ALDH1A1MAPTMEN1KMT2AKDM4E
SCHEMBL23434665 0.94 MEN1 (0.46) ALDH1A1MAPTMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8053176-B2 irradiation of a polynuclear phenanthroline derivative such as (1,4-di(1,10-phenanthroline-2-yl)benzene layer between transparent counter electrodes, while controlling the radiation intensity, to form an emission pattern having contrast caused by the luminous brightness YAMAGATA PROMOTIONAL ORGANIZATION FOR INDUSTRIAL TECHNOLOGY (JP) 2011-11-08 US disclosed
US-8053176-B2 irradiation of a polynuclear phenanthroline derivative such as (1,4-di(1,10-phenanthroline-2-yl)benzene layer between transparent counter electrodes, while controlling the radiation intensity, to form an emission pattern having contrast caused by the luminous brightness YAMAGATA PROMOTIONAL ORGANIZATION FOR INDUSTRIAL TECHNOLOGY (JP) 2011-11-08 US disclosed
US-20080131816-A1 PATTERNING METHOD OF ORGANIC ELECTROLUMINESCENT DEVICE YAMAGATA PROMOTIONAL ORGANIZATION FOR INDUSTRIAL TECHNOLOGY (JP) 2008-06-05 US disclosed
US-20080131816-A1 PATTERNING METHOD OF ORGANIC ELECTROLUMINESCENT DEVICE YAMAGATA PROMOTIONAL ORGANIZATION FOR INDUSTRIAL TECHNOLOGY (JP) 2008-06-05 US disclosed
EP-1928040-A2 Patterning method of organic electroluminescent device Yamagata Promotional Organization for Industrial Technology (JP) 2008-06-04 EP disclosed