SCHEMBL12112866

SCHEMBL12112866

Cc1ccc(N(c2ccc(C)cc2)c2ccc(-c3cccc(-c4cnc5ccccc5c4)c3)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BIRC5 O15392 1/20 0.55
MAP4K4 O95819 1/20 0.52
CSNK1G2 P78368 1/20 0.52
CLK4 Q9HAZ1 1/20 0.52
MKNK2 Q9HBH9 1/20 0.52
MAP4K5 Q9Y4K4 1/20 0.52
PDGFRB P09619 3/20 0.51
PDGFRA P16234 3/20 0.51
PIK3CD O00329 3/20 0.50
PIK3CA P42336 2/20 0.50
CYP2A6 P11509 1/20 0.49
CYP1A2 P05177 1/20 0.49
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA9 Q16790 1/20 0.48
NPC1 O15118 3/20 0.47
RAB9A P51151 3/20 0.47
MAPT P10636 2/20 0.47
ALDH1A1 P00352 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8370258 0.87 PDGFRB (0.66) BIRC5MAP4K4CSNK1G2CLK4MKNK2
SCHEMBL23555381 0.87 PDGFRB (0.66) BIRC5MAP4K4CSNK1G2CLK4MKNK2
SCHEMBL24229569 0.87 PDGFRB (0.66) BIRC5MAP4K4CSNK1G2CLK4MKNK2
SCHEMBL24229577 0.87 PDGFRB (0.66) BIRC5MAP4K4CSNK1G2CLK4MKNK2
SCHEMBL18325317 0.86 MAP4K4 (0.58) BIRC5MAP4K4CSNK1G2CLK4MKNK2
SCHEMBL26550770 0.85 PDGFRB (0.60) BIRC5MAP4K4CSNK1G2CLK4MKNK2
SCHEMBL23204767 0.84 PDGFRB (0.58) BIRC5MAP4K4CSNK1G2CLK4MKNK2
SCHEMBL26560525 0.84 PDGFRB (0.58) BIRC5MAP4K4CSNK1G2CLK4MKNK2
SCHEMBL18325345 0.82 PDGFRB (0.53) BIRC5MAP4K4CSNK1G2CLK4MKNK2
SCHEMBL18325231 0.82 PDGFRB (0.53) BIRC5MAP4K4CSNK1G2CLK4MKNK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8053090-B2 Phosphorescent multinuclear copper complex and organic electroluminescent device using the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-11-08 US disclosed
US-20070270592-A1 Phosphorescent multinuclear copper complex and organic electroluminescent device using the same SAMSUNG DISPLAY CO., LTD. (KR) 2007-11-22 US disclosed