SCHEMBL8370258

SCHEMBL8370258

Cc1ccc(-c2cnc3ccccc3c2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDGFRB P09619 3/20 0.66
PDGFRA P16234 3/20 0.66
CYP1A2 P05177 1/20 0.63
CA12 O43570 1/20 0.59
CA1 P00915 1/20 0.59
CA2 P00918 1/20 0.59
CA9 Q16790 1/20 0.59
PIK3CD O00329 2/20 0.58
PIK3CA P42336 2/20 0.58
NPC1 O15118 4/20 0.57
RAB9A P51151 4/20 0.57
MAPT P10636 2/20 0.57
ALDH1A1 P00352 2/20 0.57
CYP2A6 P11509 1/20 0.57
BIRC5 O15392 1/20 0.56
MAP4K4 O95819 1/20 0.53
CSNK1G2 P78368 1/20 0.53
CLK4 Q9HAZ1 1/20 0.53
MKNK2 Q9HBH9 1/20 0.53
MAP4K5 Q9Y4K4 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23555381 1.00 PDGFRB (0.66) PDGFRBPDGFRACYP1A2CA12CA1
SCHEMBL26550770 0.95 PDGFRB (0.60) PDGFRBPDGFRACYP1A2CA12CA1
SCHEMBL26560525 0.93 PDGFRB (0.58) PDGFRBPDGFRACYP1A2CA12CA1
SCHEMBL27430960 0.89 PDGFRB (0.62) PDGFRBPDGFRACYP1A2CA12CA1
SCHEMBL18325345 0.88 PDGFRB (0.53) PDGFRBPDGFRACYP1A2CA12CA1
SCHEMBL18325231 0.88 PDGFRB (0.53) PDGFRBPDGFRACYP1A2CA12CA1
SCHEMBL12112866 0.87 BIRC5 (0.55) PDGFRBPDGFRACYP1A2CA12CA1
SCHEMBL29375510 0.86 PDGFRB (0.72) PDGFRBPDGFRACYP1A2CA12CA1
SCHEMBL24621829 0.86 PDGFRB (0.72) PDGFRBPDGFRACYP1A2CA12CA1
SCHEMBL26829682 0.86 PDGFRB (0.72) PDGFRBPDGFRACYP1A2CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115710223-B Preparation method of 3-aryl quinolinone derivative 广东工业大学 2024-05-10 CN disclosed
CN-117003695-A Preparation method of 2, 3-disubstituted quinoline derivative 广东工业大学 2023-11-07 CN disclosed
US-11770974-B2 P active materials for organic photoelectric conversion layers in organic photodiodes SONY CORPORATION (JP) 2023-09-26 US disclosed
US-11770974-B2 P active materials for organic photoelectric conversion layers in organic photodiodes SONY CORPORATION (JP) 2023-09-26 US disclosed
CN-116655529-A Method for synthesizing 3-aryl quinoline compound by nickel catalysis 湖南大学 2023-08-29 CN disclosed
CN-114031552-A Method for synthesizing substituted quinoline derivative from aromatic aldehyde and aromatic amine participated in DMSO 长沙资材科技有限公司 2022-02-11 CN disclosed
US-20210193935-A1 P ACTIVE MATERIALS FOR ORGANIC PHOTOELECTRIC CONVERSION LAYERS IN ORGANIC PHOTODIODES SONY CORPORATION (JP) 2021-06-24 US disclosed
WO-2020085319-A1 CYCLIC AZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2020-04-30 WO disclosed
US-8735577-B2 1,3,5-triazine derivative, process for producing same, and organic electroluminescent element comprising same as constituent component TOSOH CORPORATION (JP) 2014-05-27 US disclosed
US-20110190494-A1 1,3,5-TRIAZINE DERIVATIVE, PROCESS FOR PRODUCING SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME AS CONSTITUENT COMPONENT TOSOH CORPORATION (JP) 2011-08-04 US disclosed
US-20100133995-A1 Novel thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium FUJI XEROX CO., LTD. (JP) 2010-06-03 US disclosed
US-20100133995-A1 Novel thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium FUJI XEROX CO., LTD. (JP) 2010-06-03 US disclosed
US-20100137553-A1 Novel thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium FUJI XEROX CO., LTD. (JP) 2010-06-03 US disclosed
US-7659410-B2 Thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium FUJI XEROX CO., LTD. (JP) 2010-02-09 US disclosed
US-7659410-B2 Thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium FUJI XEROX CO., LTD. (JP) 2010-02-09 US disclosed
US-7455916-B2 Organic electroluminescent element FUJI XEROX CO., LTD. (JP) 2008-11-25 US disclosed
US-20070252519-A1 Novel thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium FUJI XEROX CO., LTD. (JP) 2007-11-01 US disclosed
US-20070252519-A1 Novel thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium FUJI XEROX CO., LTD. (JP) 2007-11-01 US disclosed
US-7166859-B2 Organic semiconductor transistor element, semiconductor device using the same, and process for producing the semiconductor device FUJI XEROX CO., LTD. (JP) 2007-01-23 US disclosed
WO-2003033671-A2 HUMAN GLUCAGON-LIKE-PEPTIDE-1 MIMICS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS BRISTOL-MYERS SQUIBB COMPANY (US) 2003-04-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110190494-A1 1,3,5-TRIAZINE DERIVATIVE, PROCESS FOR PRODUCING SAME, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME AS CONSTITUENT COMPONENT ASH2L, SETDB1, KAT5 PDGFRB 4076/4885PDGFRA 3509/4885CYP1A2 466/4885
US-11770974-B2 P active materials for organic photoelectric conversion layers in organic photodiodes JUP, L1CAM, EPCAM PDGFRB 3645/4885PDGFRA 3252/4885CYP1A2 1899/4885
US-20070252519-A1 Novel thiophene-containing compound and thiophene-containing compound polymer, organic electroluminescent device, production method thereof, and image display medium ARL1, NOD1, NLRP1 PDGFRB 3717/4885PDGFRA 4028/4885CYP1A2 1496/4885
US-20210193935-A1 P ACTIVE MATERIALS FOR ORGANIC PHOTOELECTRIC CONVERSION LAYERS IN ORGANIC PHOTODIODES JUP, L1CAM, EPCAM PDGFRB 3645/4885PDGFRA 3252/4885CYP1A2 1899/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.