SCHEMBL12112960

SCHEMBL12112960

CNC(=O)c1cc(C#N)cc(C)c1NC(=O)c1cc(Cn2cc(C(C)(C)C)nn2)nn1-c1ncccc1Cl

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 5/20 0.33
SLC2A3 P11169 5/20 0.33
SLC2A4 P14672 5/20 0.33
SLC2A2 P11168 1/20 0.33
DHODH Q02127 1/20 0.32
KLKB1 P03952 1/20 0.31
KDM5B Q9UGL1 1/20 0.31
CDC25A P30304 1/20 0.31
CDC25B P30305 1/20 0.31
CDC25C P30307 1/20 0.31
PIN1 Q13526 1/20 0.30
PDE4A P27815 1/20 0.30
PDE4B Q07343 1/20 0.30
PDE4C Q08493 1/20 0.30
PDE4D Q08499 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12113363 0.94 SLC2A1 (0.37) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL12113005 0.94 SLC2A1 (0.33) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL12117282 0.93 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL12113462 0.93 SLC2A1 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL12112932 0.92 DHODH (0.33) DHODHCDC25ACDC25BCDC25C
SCHEMBL12117091 0.91 SLC2A1 (0.34) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL12112957 0.90 KCNH2 (0.35) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL12113379 0.89 SLC2A1 (0.36) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL12112966 0.88 CDC25A (0.33) SLC2A1SLC2A3SLC2A4SLC2A2DHODH
SCHEMBL12112962 0.88 NR1I3 (0.37) KLKB1KDM5BPIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8536202-B2 Triazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2013-09-17 US disclosed
US-8536202-B2 Triazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2013-09-17 US disclosed
US-20110275676-A1 Triazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2011-11-10 US disclosed
US-20110275676-A1 Triazole-substituted anthranilamides as pesticides BAYER CROPSCIENCE AG (DE) 2011-11-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275676-A1 Triazole-substituted anthranilamides as pesticides AADAC, NAAA, ANTXR2 SLC2A1 4803/4885SLC2A3 4685/4885SLC2A4 4817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.