Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 10/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | TMIGD3 | P0DMS9 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.41 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 5/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.39 |
| ▸ | PDE1A | P54750 | 1/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12112259 | 0.93 | ADORA2A (0.54) | ADORA2AADORA1ADORA2BHTR2CTMIGD3 | |
| SCHEMBL12112260 | 0.87 | ADORA2A (0.54) | ADORA2AADORA1ADORA2BHTR2CTMIGD3 | |
| SCHEMBL12112262 | 0.85 | ADORA2A (0.49) | ADORA2AADORA1ADORA2BHTR2CTMIGD3 | |
| SCHEMBL15214197 | 0.85 | ADORA2A (0.49) | ADORA2AADORA1ADORA2BHTR2CTMIGD3 | |
| SCHEMBL12112265 | 0.85 | ADORA2A (0.49) | ADORA2AADORA1ADORA2BHTR2CTMIGD3 | |
| SCHEMBL12112261 | 0.85 | ADORA2A (0.52) | ADORA2AADORA1ADORA2BHTR2CTMIGD3 | |
| SCHEMBL15214199 | 0.85 | ADORA2A (0.49) | ADORA2AADORA1ADORA2BHTR2CTMIGD3 | |
| SCHEMBL12112263 | 0.85 | ADORA2A (0.49) | ADORA2AADORA1ADORA2BHTR2CTMIGD3 | |
| SCHEMBL12113561 | 0.79 | GSK3B (0.40) | ADORA2AADORA1ADORA2BPI4KAPI4K2B | |
| SCHEMBL12113563 | 0.78 | ADORA2A (0.42) | ADORA2AADORA1ADORA2BCYP1A2PI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110275588-A1 | Fused Diimidazodiazepine Compounds and Methods of Use and Manufacture Thereof | HOSMANE, RAMACHANDRA S. | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275588-A1 | Fused Diimidazodiazepine Compounds and Methods of Use and Manufacture Thereof | IKZF3, AADAC, IKBKE | ADORA2A 2862/4885ADORA1 3039/4885ADORA2B 2714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.