Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.37 |
| ▸ | AHCY | P23526 | 2/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.35 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12113560 | 0.92 | ADORA2A (0.38) | ADORA2AADORA1ADORA2BADORA3CCNE1 | |
| SCHEMBL13394059 | 0.81 | CYP3A4 (0.38) | ADORA2AADORA1CYP3A4ALDH1A1CYP2D6 | |
| SCHEMBL13393953 | 0.79 | CYP3A4 (0.35) | ADORA2AADORA1ADORA2BCYP3A4ALDH1A1 | |
| SCHEMBL12112259 | 0.79 | ADORA2A (0.54) | ADORA2AADORA1ADORA2BALDH1A1PI4KA | |
| SCHEMBL12113559 | 0.78 | ADORA2A (0.52) | ADORA2AADORA1ADORA2BCCNE1CDK2 | |
| SCHEMBL15214188 | 0.77 | ALDH1A1 (0.38) | ADORA2AADORA1ADORA2BCYP3A4ALDH1A1 | |
| SCHEMBL15214187 | 0.77 | ALDH1A1 (0.38) | ADORA2AADORA1ADORA2BCYP3A4ALDH1A1 | |
| SCHEMBL12112260 | 0.76 | ADORA2A (0.54) | ADORA2AADORA1ADORA2BALDH1A1TLR7 | |
| SCHEMBL15214197 | 0.74 | ADORA2A (0.49) | ADORA2AADORA1ADORA2BALDH1A1TLR7 | |
| SCHEMBL12112261 | 0.74 | ADORA2A (0.52) | ADORA2AADORA1ADORA2BALDH1A1TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110275588-A1 | Fused Diimidazodiazepine Compounds and Methods of Use and Manufacture Thereof | HOSMANE, RAMACHANDRA S. | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275588-A1 | Fused Diimidazodiazepine Compounds and Methods of Use and Manufacture Thereof | IKZF3, AADAC, IKBKE | ADORA2A 2862/4885ADORA1 3039/4885ADORA2B 2714/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.