SCHEMBL12124129

SCHEMBL12124129

CCc1c2ccccc2c(C23CC4CC(CC(COC(=O)C(F)(F)S(=O)(=O)O)(C4)C2)C3)c2ccccc12

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 2/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL686240 0.91 KMT2A (0.33) SCN9AMEN1KMT2A
SCHEMBL12128683 0.89 MEN1 (0.36) MEN1KMT2A
SCHEMBL12124132 0.84 KMT2A (0.31) SCN9AKMT2A
SCHEMBL12121548 0.83
SCHEMBL12727402 0.82 LMNA (0.41) MEN1KMT2A
SCHEMBL686548 0.81 KMT2A (0.34) SCN9AMEN1KMT2A
SCHEMBL12389596 0.81 KMT2A (0.34) SCN9AMEN1KMT2A
SCHEMBL686558 0.81 MEN1 (0.40) MEN1KMT2A
SCHEMBL686584 0.80 MEN1 (0.34) SCN9AMEN1KMT2A
SCHEMBL686610 0.79 MEN1 (0.50) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8298746-B2 Chemically amplified positive resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-30 US disclosed
US-8062830-B2 Chemically amplified positive resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-22 US disclosed
US-8057983-B2 liquid immersion lithography, solves problem of defect caused by residual fluid droplets on the resist film; blend of resin containing no fluorine and acid labile group, and an acrylic fluoro-copolymer with units of a fluoromonomer and units of acid labile, lactone, or hydroxy-functional group SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-15 US disclosed
US-20100010129-A1 CHEMICALLY AMPLIFIED POSITIVE RESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-01-14 US disclosed
US-20090269695-A1 CHEMICALLY AMPLIFIED POSITIVE RESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-29 US disclosed