Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 13/20 | 0.72 |
| ▸ | MAOA | P21397 | 5/20 | 0.72 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.72 |
| ▸ | SDHA | P31040 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | CALML3 | P27482 | 1/20 | 0.72 |
| ▸ | F10 | P00742 | 6/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12006777 | 1.00 | MAOB (0.72) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL12006775 | 1.00 | MAOB (0.72) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL14214166 | 0.91 | MAOB (0.70) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL12176864 | 0.89 | MAOB (0.70) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL13316509 | 0.89 | MAOB (0.58) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL23699727 | 0.88 | MAOB (0.69) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL12478205 | 0.88 | MAOB (0.69) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL2583967 | 0.88 | MAOB (0.69) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL2872739 | 0.88 | MAOB (0.69) | MAOBMAOAPTGS1SDHALMNA | |
| SCHEMBL2829207 | 0.88 | MAOB (0.72) | MAOBMAOAPTGS1SDHALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9656973-B2 | Processes for preparing linezolid | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2017-05-23 | — | — | US | disclosed |
| US-9376407-B2 | Process for preparation of Linezolid and its novel intermediates | LEE PHARMA LIMITED (IN) | 2016-06-28 | — | — | US | disclosed |
| US-20160024032-A1 | PROCESSES FOR PREPARING LINEZOLID | UNIV INDIANA RES & TECH CORP (US) | 2016-01-28 | — | — | US | disclosed |
| US-9206141-B2 | Processes for preparing linezolid | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2015-12-08 | — | — | US | disclosed |
| US-8962827-B2 | Linezolid intermediate and method for synthesizing linezolid | ZHEJIANG MEDICINE CO. LTD. XINCHANG PHARMACEUTICAL FACTORY (CN) | 2015-02-24 | — | — | US | disclosed |
| WO-2014170908-A1 | PROCESS FOR PREPARATION OF OXAZOLIDINONE DERIVATIVES | NOSCH LABS PRIVATE LIMITED (IN) | 2014-10-23 | — | — | WO | disclosed |
| US-20130137864-A1 | PROCESS FOR THE PREPARATION OF LINEZOLID | ALEMBIC PHARMACEUTICALS, LTD. (IN) | 2013-05-30 | — | — | US | disclosed |
| US-20130053557-A1 | PROCESSES FOR PREPARING LINEZOLID | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2013-02-28 | — | — | US | disclosed |
| US-20110275805-A1 | METHOD FOR PREPARING LINEZOLID AND INTERMEDIATES THEREOF | LIANHE CHEMICAL TECHNOLOGY CO., LTD. (CN) | 2011-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024032-A1 | PROCESSES FOR PREPARING LINEZOLID | CYP2C9, CYP2C19, CYP3A43 | MAOB 1936/4885MAOA 1768/4885PTGS1 3373/4885 |
| US-20130137864-A1 | PROCESS FOR THE PREPARATION OF LINEZOLID | CYP3A5, CYP2C9, CYP2C19 | MAOB 348/4885MAOA 343/4885PTGS1 2618/4885 |
| US-20110275805-A1 | METHOD FOR PREPARING LINEZOLID AND INTERMEDIATES THEREOF | HDAC9, KAT5, ACMSD | MAOB 2466/4885MAOA 2149/4885PTGS1 3624/4885 |
| US-20130053557-A1 | PROCESSES FOR PREPARING LINEZOLID | CYP2C9, CYP2C19, CYP3A43 | MAOB 1936/4885MAOA 1768/4885PTGS1 3373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.