SCHEMBL12128652

SCHEMBL12128652

CC(F)(F)C(=O)OCC1CC2C=CC1C2

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 12/20 0.36
ALDH1A1 P00352 5/20 0.36
PKM P14618 3/20 0.34
MAPT P10636 1/20 0.34
MAPK1 P28482 1/20 0.34
POLB P06746 1/20 0.34
ALOX15 P16050 1/20 0.34
TDP1 Q9NUW8 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
HTT P42858 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
ATM Q13315 1/20 0.32
EPHX2 P34913 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25689244 0.91 KDM4E (0.36) KDM4EALDH1A1PKMMAPTMAPK1
SCHEMBL22883585 0.91 KDM4E (0.36) KDM4EALDH1A1PKMMAPTMAPK1
SCHEMBL32688573 0.88 KDM4E (0.38) KDM4EALDH1A1PKMMAPTMAPK1
SCHEMBL24183481 0.85 KDM4E (0.36) KDM4EALDH1A1PKMMAPTMAPK1
SCHEMBL24142269 0.84 KDM4E (0.33) KDM4EALDH1A1PKMPOLBALOX15
SCHEMBL12922446 0.82 KDM4E (0.33) KDM4EALDH1A1PKMPOLBALOX15
SCHEMBL12922447 0.82 KDM4E (0.33) KDM4EALDH1A1PKMPOLBALOX15
SCHEMBL10332359 0.81 KDM4E (0.37) KDM4EALDH1A1PKMMAPTMAPK1
SCHEMBL2606007 0.81 KDM4E (0.37) KDM4EALDH1A1PKMPOLBALOX15
SCHEMBL12460487 0.81 KDM4E (0.31) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8329838-B2 Norbornene-type polymers, compositions thereof and lithographic processes using such compositions PROMERUS LLC (US) 2012-12-11 US disclosed
US-8062830-B2 Chemically amplified positive resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-22 US disclosed
US-20110189618-A1 RESIST PROCESSING METHOD SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-04 US disclosed
US-20110183264-A1 RESIST PROCESSING METHOD AND USE OF POSITIVE TYPE RESIST COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-28 US disclosed
US-20110171586-A1 RESIST PROCESSING METHOD SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-14 US disclosed
US-20110091820-A1 RESIST PROCESSING METHOD SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-21 US disclosed
US-20110091818-A1 PROCESS FOR PRODUCING PHOTORESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-04-21 US disclosed
US-20110065878-A1 Norbornene-Type Polymers, Compositions Thereof And Lithographic Processes Using Such Compositions PROMERUS LLC (US) 2011-03-17 US disclosed