SCHEMBL12460487

SCHEMBL12460487

CC(C(F)(F)F)(C(F)(F)F)C(F)(F)C(F)(C(F)(F)F)C(F)(F)C(=O)OCC1CC2C=CC1C2

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13237650 0.90 KDM4E (0.31) KDM4E
SCHEMBL12634106 0.89 KDM4E (0.30) KDM4E
SCHEMBL12634108 0.88 KDM4E (0.30) KDM4E
SCHEMBL146170 0.81 CA1 (0.37) KDM4E
SCHEMBL25689244 0.81 KDM4E (0.36) KDM4E
SCHEMBL22883585 0.81 KDM4E (0.36) KDM4E
SCHEMBL12128652 0.81 KDM4E (0.36) KDM4E
SCHEMBL32688573 0.78 KDM4E (0.38) KDM4E
SCHEMBL13237655 0.78 KDM4E (0.33) KDM4E
SCHEMBL24142269 0.77 KDM4E (0.33) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1853972-B1 NORBORNENE-TYPE POLYMERS AND THEIR MANUFACTURE PROCESS PROMERUS LLC (US) 2011-07-20 EP disclosed