Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | CCR8 | P51685 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | AGER | Q15109 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12132293 | 0.82 | CCR1 (0.39) | CCR1CCR5CCR8HDAC6TGFBR1 | |
| SCHEMBL12622282 | 0.78 | CCR1 (0.71) | CCR1CCR5CCR8HDAC6MAPT | |
| SCHEMBL12132272 | 0.78 | CYP1A2 (0.47) | MAPTLMNAHTTCYP3A4KDM4E | |
| SCHEMBL22926721 | 0.77 | KDM4E (0.43) | MAPTLMNAHTTCYP3A4KDM4E | |
| SCHEMBL12132298 | 0.76 | NPC1 (0.46) | CCR1CCR5CCR8HDAC6MAPT | |
| SCHEMBL14780608 | 0.76 | KDM4E (0.46) | CCR1CCR5CCR8HDAC6MAPT | |
| SCHEMBL24657742 | 0.75 | CYP1A1 (0.49) | MAPTLMNAHTTL3MBTL1TDP1 | |
| SCHEMBL22373647 | 0.74 | CYP1A2 (0.47) | MAPTLMNAHTTCYP3A4KDM4E | |
| SCHEMBL25777662 | 0.74 | KDM4E (0.57) | CCR1CCR5CCR8MAPTLMNA | |
| SCHEMBL16547031 | 0.74 | GRIN2D (0.44) | CCR1CCR5CCR8HDAC6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110284829-A1 | POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-24 | — | — | US | disclosed |