Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.46 |
| ▸ | RELA | Q04206 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RORA | P35398 | 3/20 | 0.38 |
| ▸ | RORC | P51449 | 3/20 | 0.38 |
| ▸ | RORB | Q92753 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CCR8 | P51685 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12132279 | 0.83 | ADORA3 (0.42) | NPC1RAB9ASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL12132282 | 0.83 | RAB9A (0.48) | NPC1RAB9ASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL12132293 | 0.78 | CCR1 (0.39) | TP53CCR1CCR5CCR8HDAC6 | |
| SCHEMBL11976546 | 0.76 | RAB9A (0.50) | NPC1RAB9ASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL12132295 | 0.76 | CCR1 (0.44) | L3MBTL1CCR1CCR5CCR8HDAC6 | |
| SCHEMBL12132288 | 0.74 | UCHL3 (0.46) | NPC1RAB9ASMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL26730681 | 0.73 | RORA (0.43) | RORARORCRORBPGRPSMB5 | |
| SCHEMBL23118981 | 0.73 | PSMB5 (0.40) | RORARORCRORBPGRPSMB5 | |
| SCHEMBL12132283 | 0.73 | ICMT (0.43) | NPC1RAB9ASMN1; SMN2RORARORC | |
| SCHEMBL23118777 | 0.72 | PSMB5 (0.40) | RORARORCRORBPGRPSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110284829-A1 | POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-11-24 | — | — | US | disclosed |