Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1D | O15297 | 3/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15827347 | 1.00 | PPM1D (0.77) | PPM1D | |
| SCHEMBL12143691 | 0.92 | PPM1D (0.77) | PPM1D | |
| SCHEMBL12427640 | 0.81 | PPM1D (0.49) | PPM1D | |
| SCHEMBL12143695 | 0.75 | PPM1D (0.47) | PPM1D | |
| SCHEMBL15827346 | 0.75 | PPM1D (0.47) | PPM1D | |
| SCHEMBL12143694 | 0.73 | PPM1D (0.54) | PPM1D | |
| SCHEMBL12143689 | 0.70 | PPM1D (0.50) | PPM1D | |
| SCHEMBL12143692 | 0.64 | PPM1D (0.44) | PPM1D | |
| SCHEMBL8903439 | 0.58 | PPM1D (0.36) | PPM1D | |
| SCHEMBL8540123 | 0.58 | PPM1D (0.36) | PPM1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8759323-B2 | Protein phosphatase inhibitor | LSIP, LLC (JP) | 2014-06-24 | — | — | US | disclosed |
| US-20110288050-A1 | PROTEIN PHOSPHATASE INHIBITOR | LSIP, LLC (JP) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288050-A1 | PROTEIN PHOSPHATASE INHIBITOR | PPM1A, PPM1F, PPM1G | PPM1D 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.