SCHEMBL8540123

SCHEMBL8540123

CC(C)(C)[Si](C)(C)O[C@@H]1C[C@](O)(CO)C[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]1O

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PPM1D O15297 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8903439 1.00 PPM1D (0.36) PPM1D
SCHEMBL17340158 0.84 PPM1D (0.33) PPM1D
SCHEMBL12397939 0.78 PPM1D (0.34) PPM1D
SCHEMBL26323710 0.78 PPM1D (0.44) PPM1D
SCHEMBL3186681 0.78 PPM1D (0.44) PPM1D
SCHEMBL3177924 0.75 PPM1D (0.37) PPM1D
SCHEMBL6061169 0.74 STAT3 (0.33) PPM1D
SCHEMBL4195541 0.74 STAT3 (0.33) PPM1D
SCHEMBL2689416 0.74 STAT3 (0.33) PPM1D
SCHEMBL8901744 0.73 PPM1D (0.38) PPM1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0516410-B1 Novel synthesis of 19-nor vitamin D compounds WISCONSIN ALUMNI RES FOUND (US) 1998-07-29 EP disclosed
US-5581006-A Synthesis of 19-nor vitamin D compounds WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1996-12-03 US disclosed
US-5563286-A Synthesis of 19-nor vitamin D compounds WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1996-10-08 US disclosed
EP-0619306-B1 19-Nor-vitamin D3 compounds with substituent at 2-position WISCONSIN ALUMNI RES FOUND (US) 1996-09-11 EP disclosed
EP-0516411-B1 Intermediates for the synthesis of 19-nor vitamin D compounds WISCONSIN ALUMNI RES FOUND (US) 1996-02-21 EP disclosed
US-5486636-A Synthesis of 19-nor vitamin D compounds WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1996-01-23 US disclosed
US-5391755-A Synthesis of 19-NOR vitamin D compounds WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1995-02-21 US disclosed
EP-0619306-A1 19-Nor-vitamin D3 compounds with substituent at 2-position WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1994-10-12 EP disclosed
EP-0516411-A1 Intermediates for the synthesis of 19-nor vitamin D compounds WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1992-12-02 EP disclosed
EP-0516410-A2 Novel synthesis of 19-nor vitamin D compounds WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1992-12-02 EP disclosed