SCHEMBL12153253

SCHEMBL12153253

Cc1ccc(C(c2ccc(N3C(=O)c4ccc(Oc5ccc6c(c5)C(=O)N(C)C6=O)cc4C3=O)c(O)c2)(C(F)(F)F)C(F)(F)F)cc1O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.39
ESR2 Q92731 2/20 0.39
BRD4 O60885 1/20 0.38
ALDH1A1 P00352 5/20 0.37
MEN1 O00255 5/20 0.37
KMT2A Q03164 5/20 0.37
GAA P10253 1/20 0.37
PKM P14618 1/20 0.36
KDM4E B2RXH2 2/20 0.35
HTT P42858 2/20 0.35
POLB P06746 1/20 0.35
LPAR1 Q92633 1/20 0.35
LPAR3 Q9UBY5 1/20 0.35
MAPK1 P28482 1/20 0.34
HSD17B10 Q99714 1/20 0.34
NR1H2 P55055 2/20 0.34
NR1H3 Q13133 2/20 0.34
NPSR1 Q6W5P4 1/20 0.34
TDP1 Q9NUW8 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9999626 0.95 BRD4 (0.43) ESR1ESR2BRD4ALDH1A1MEN1
SCHEMBL12367660 0.92 ESR1 (0.43) ESR1ESR2ALDH1A1MEN1KMT2A
SCHEMBL13411188 0.89 ESR1 (0.41) ESR1ESR2BRD4ALDH1A1MEN1
SCHEMBL13292495 0.87 BRD4 (0.38) ESR1ESR2BRD4ALDH1A1MEN1
SCHEMBL13038060 0.87 ESR1 (0.41) ESR1ESR2ALDH1A1MEN1KMT2A
SCHEMBL25969184 0.85 MEN1 (0.38) ESR1ESR2BRD4ALDH1A1MEN1
SCHEMBL21933189 0.83 PKM (0.38) ESR1ESR2BRD4ALDH1A1MEN1
SCHEMBL13220607 0.82 NR1H2 (0.41) ESR1ESR2BRD4ALDH1A1MEN1
SCHEMBL17898388 0.81 BRD4 (0.47) ESR1ESR2BRD4ALDH1A1MEN1
SCHEMBL13220616 0.80 MEN1 (0.34) ESR1ESR2BRD4ALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8049033-B2 Dendrimer solid acid and polymer electrolyte membrane including the same SAMSUNG SDI CO., LTD. (KR) 2011-11-01 US disclosed
US-8003729-B2 comprising crosslinkable polyvinylalcohol, polyvinylphenol, polyhydroxyphenylmaleimide, aromatic polyimides and crosslinking agent; resist to heat and chemical; organic thin film transistor SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-08-23 US disclosed
US-20080283829-A1 Organic insulator composition including a hydroxyl group-containing polymer, dielectric film and organic thin film transistor using the same SAMSUNG ELECTRONICS CO., LTD. 2008-11-20 US disclosed
US-20080187867-A1 PHOTOSENSITIVE POLYIMIDE COMPOSITION, POLYIMIDE FILM AND SEMICONDUCTOR DEVICE USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-08-07 US disclosed
US-20070092779-A1 Dendrimer solid acid and polymer electrolyte membrane including the same SAMSUNG SDI CO., LTD. (KR) 2007-04-26 US disclosed
US-20070092778-A1 Oligomer solid acid and polymer electrolyte membrane including the same SAMSUNG SDI CO., LTD. (KR) 2007-04-26 US disclosed