SCHEMBL12154243

SCHEMBL12154243

CCC1CCC(C(=O)Oc2ccc3cc(OC(=O)C4CCC(CC)CC4)ccc3c2)CC1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.59
KMT2A Q03164 3/20 0.54
MEN1 O00255 1/20 0.54
MAPT P10636 1/20 0.54
HTT P42858 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
PDGFRB P09619 2/20 0.47
PDGFRA P16234 2/20 0.47
KDM4E B2RXH2 1/20 0.47
ALDH1A1 P00352 1/20 0.47
GLA P06280 1/20 0.47
GAA P10253 1/20 0.47
F2 P00734 1/20 0.46
CA2 P00918 1/20 0.46
ATM Q13315 1/20 0.46
ELANE P08246 1/20 0.45
POLB P06746 2/20 0.43
ABL1 P00519 1/20 0.42
HPGD P15428 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12154218 0.90 KMT2A (0.61) L3MBTL1KMT2AMEN1MAPTHTT
SCHEMBL20045170 0.90 KMT2A (0.61) L3MBTL1KMT2AMEN1MAPTHTT
SCHEMBL14192498 0.86 L3MBTL1 (0.46) L3MBTL1KMT2AMEN1MAPTHTT
SCHEMBL12154150 0.85 KMT2A (0.45) L3MBTL1KMT2AMEN1MAPTHTT
Fluoride SCHEMBL9841337 0.85 KMT2A (0.51) L3MBTL1KMT2AMEN1MAPTHTT
SCHEMBL12154151 0.84 HTT (0.54) L3MBTL1KMT2AHTTSMN1; SMN2TDP1
SCHEMBL17059002 0.84 KMT2A (0.54) L3MBTL1KMT2AMEN1MAPTHTT
SCHEMBL20443893 0.84 KMT2A (0.54) KMT2AMEN1MAPTHTTSMN1; SMN2
SCHEMBL12154220 0.84 POLB (0.45) L3MBTL1KMT2AMEN1MAPTHTT
SCHEMBL11829358 0.83 L3MBTL1 (0.75) L3MBTL1KMT2AMEN1MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8048496-B2 Polymerizable liquid crystal compound, liquid crystal composition and polymer JNC CORPORATION (JP) 2011-11-01 US disclosed
US-20100096591-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND POLYMER CHISSO CORPORATION 2010-04-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100096591-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND POLYMER PKN1, ZYX, OXER1 L3MBTL1 1227/4885KMT2A 1370/4885MEN1 823/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.