Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 1/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 16/20 | 0.49 |
| ▸ | WDR77 | Q9BQA1 | 13/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12150829 | 1.00 | ADK (0.50) | ADKPRMT5WDR77ADORA2AMETTL3 | |
| SCHEMBL12300524 | 1.00 | ADK (0.50) | ADKPRMT5WDR77ADORA2AMETTL3 | |
| SCHEMBL474927 | 1.00 | ADK (0.50) | ADKPRMT5WDR77ADORA2AMETTL3 | |
| SCHEMBL12154906 | 0.87 | ADORA2A (0.39) | ADKPRMT5WDR77ADORA2AMETTL3 | |
| SCHEMBL12150845 | 0.87 | ADK (0.56) | ADKPRMT5WDR77ADORA2AMETTL3 | |
| SCHEMBL6841559 | 0.87 | ADK (0.56) | ADKPRMT5WDR77ADORA2AMETTL3 | |
| SCHEMBL12154683 | 0.87 | ADK (0.56) | ADKPRMT5WDR77ADORA2AMETTL3 | |
| SCHEMBL731889 | 0.87 | ADK (0.56) | ADKPRMT5WDR77ADORA2AMETTL3 | |
| SCHEMBL10208018 | 0.85 | ADK (0.55) | ADKPRMT5WDR77ADORA2AMETTL3 | |
| SCHEMBL18490535 | 0.84 | PDE4D (0.57) | ADKPRMT5WDR77ADORA2AMETTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110288053-A1 | ANTIVIRAL PHOSPHONATE ANALOGS | GILEAD SCIENCES, INC. (US) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288053-A1 | ANTIVIRAL PHOSPHONATE ANALOGS | TYMP, ITPA, PNP | ADK 341/4885PRMT5 2581/4885WDR77 1899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.