Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CLPP | Q16740 | 1/20 | 0.36 |
| ▸ | TCF4 | P15884 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL749885 | 0.94 | L3MBTL1 (0.45) | POLBCYP3A4L3MBTL1MEN1KMT2A | |
| SCHEMBL746634 | 0.91 | POLB (0.45) | POLBCYP3A4MEN1KMT2ACLPP | |
| SCHEMBL747257 | 0.89 | POLB (0.49) | POLBCYP3A4MEN1KMT2ACLPP | |
| SCHEMBL12152315 | 0.89 | POLB (0.49) | POLBCYP3A4MEN1KMT2ACLPP | |
| SCHEMBL749749 | 0.89 | POLB (0.49) | POLBCYP3A4MEN1KMT2ACLPP | |
| SCHEMBL746281 | 0.88 | POLB (0.47) | POLBCYP3A4L3MBTL1MEN1KMT2A | |
| SCHEMBL747001 | 0.88 | POLB (0.42) | POLBCYP3A4L3MBTL1MEN1KMT2A | |
| SCHEMBL750868 | 0.88 | L3MBTL1 (0.46) | POLBCYP3A4L3MBTL1MEN1KMT2A | |
| SCHEMBL748489 | 0.88 | POLB (0.42) | POLBCYP3A4L3MBTL1MEN1KMT2A | |
| SCHEMBL12154053 | 0.87 | L3MBTL1 (0.53) | POLBCYP3A4L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8049008-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2011-11-01 | — | — | US | disclosed |
| US-8049008-B2 | Reverse-turn mimetics and method relating thereto | CHOONGWAE PHARMA CORPORATION (KR) | 2011-11-01 | — | — | US | disclosed |