SCHEMBL12155397

SCHEMBL12155397

O=C(OCC1c2ccccc2-c2ccccc21)N(CO)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FABP5 Q01469 3/20 0.48
FABP7 O15540 2/20 0.48
KMT2A Q03164 2/20 0.46
EPHX2 P34913 1/20 0.43
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
OPRD1 P41143 1/20 0.39
CASP3 P42574 2/20 0.39
MDM4 O15151 1/20 0.37
TP53 P04637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL900046 0.90 KMT2A (0.47) FABP5FABP7KMT2AEPHX2CA1
SCHEMBL7690563 0.88 FABP5 (0.45) FABP5FABP7KMT2AEPHX2CA1
SCHEMBL12179490 0.87 FABP5 (0.47) FABP5FABP7KMT2AEPHX2CA1
SCHEMBL12179757 0.85 FABP5 (0.46) FABP5FABP7KMT2AEPHX2CA1
SCHEMBL8011283 0.84 SMN1; SMN2 (0.47) FABP5FABP7KMT2AEPHX2OPRD1
Formaldehyde SCHEMBL21333883 0.84 FABP5 (0.44) FABP5FABP7KMT2AEPHX2OPRD1
SCHEMBL1622971 0.83 KMT2A (0.44) FABP5FABP7KMT2AEPHX2CA1
SCHEMBL3818461 0.83 EPHX2 (0.44) FABP5FABP7KMT2AEPHX2CA1
SCHEMBL3820525 0.82 FABP5 (0.46) FABP5FABP7KMT2AEPHX2CA1
SCHEMBL3812973 0.82 PTGIR (0.43) FABP5FABP7KMT2AEPHX2CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011140393-A1 CONTROLLED RELEASE FROM MACROMOLECULAR CONJUGATES PROLYNX LLC (US) 2011-11-10 WO disclosed