SCHEMBL900046

SCHEMBL900046

O=C(O)CN(C(=O)OCC1c2ccccc2-c2ccccc21)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.47
FABP5 Q01469 3/20 0.47
FABP7 O15540 2/20 0.47
EPHX2 P34913 1/20 0.42
CASP3 P42574 2/20 0.41
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
OPRD1 P41143 1/20 0.39
PTGIR P43119 1/20 0.39
PTGDR Q13258 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3818461 0.92 EPHX2 (0.44) KMT2AFABP5FABP7EPHX2CASP3
SCHEMBL1622971 0.92 KMT2A (0.44) KMT2AFABP5FABP7EPHX2CASP3
SCHEMBL5847171 0.91 KMT2A (0.43) KMT2AFABP5FABP7EPHX2CASP3
SCHEMBL3820525 0.91 FABP5 (0.46) KMT2AFABP5FABP7EPHX2CASP3
SCHEMBL3812973 0.91 PTGIR (0.43) KMT2AFABP5FABP7EPHX2CASP3
SCHEMBL3817315 0.91 PTGIR (0.43) KMT2AFABP5FABP7EPHX2CASP3
SCHEMBL12155397 0.90 FABP5 (0.48) KMT2AFABP5FABP7EPHX2CASP3
SCHEMBL7690563 0.89 FABP5 (0.45) KMT2AFABP5FABP7EPHX2CASP3
SCHEMBL3822341 0.89 EPHX2 (0.53) KMT2AFABP5FABP7EPHX2CASP3
SCHEMBL27696345 0.89 KMT2A (0.44) KMT2AFABP5FABP7EPHX2CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106188231-B Synthesis and application of pasireotide pentapeptide intermediate 中国医学科学院药物研究所 2021-10-22 CN claimed
CN-106188231-A The synthesis of pasireotide pentapeptide intermediate and application 中国医学科学院药物研究所 2016-12-07 CN claimed
US-20260124312-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 BICYCLETX LIMITED (GB) 2026-05-07 US disclosed
US-20260036595-A1 STRUCTURE-BASED PEPTIDES FOR DETECTION OF TRANSTHYRETIN AMYLOID FIBRILS AND AGGREGATES IN PREECLAMPSIA THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2026-02-05 US disclosed
US-20260022142-A1 MACROCYCLIC IMMUNOMODULATORS BRISTOL MYERS SQUIBB CO (US) 2026-01-22 US disclosed
US-20250362310-A1 STRUCTURE-BASED PROBE FOR DETECTION OF TRANSTHYRETIN AMYLOID FIBRILS AND AGGREGATES THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-11-27 US disclosed
EP-3727462-B1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 BICYCLERD LTD (GB) 2025-11-05 EP disclosed
EP-4582436-A2 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 BicycleTX Limited (GB) 2025-07-09 EP disclosed
EP-3727461-B1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 BICYCLETX LTD (GB) 2025-07-09 EP disclosed
CN-115066417-B Factor XIa inhibitors 上海京新生物医药有限公司 2025-05-02 CN disclosed
EP-4526323-A1 MACROCYCLIC IMMUNOMODULATORS Bristol-Myers Squibb Company (US) 2025-03-26 EP disclosed
US-5763570-A Glutathione analogs and paralog panels comprising glutathione mimics TERRAPIN TECHNOLOGIES, INC. (US) 1998-06-09 US disclosed
WO-1997040034-A1 SOLID PHASE AND COMBINATORIAL SYNTHESIS OF SUBSTITUTED THIOPHENES AND OF ARRAYS OF SUBSTITUTED THIOPHENES NOVO NORDISK A/S (DK) 1997-10-30 WO disclosed
WO-1997040030-A1 SOLID PHASE AND COMBINATORIAL SYNTHESIS OF SUBSTITUTED 2-METHYLENE-2,3-DIHYDROTHIAZOLES AND OF ARRAYS OF SUBSTITUTED 2-METHYLENE-2,3-DIHYDROTHIAZOLES NOVO NORDISK A/S (DK) 1997-10-30 WO disclosed
WO-1997040025-A1 SOLID PHASE AND COMBINATORIAL SYNTHESIS OF SUBSTITUTED 1,2,3-TRIAZOLES AND OF ARRAYS OF SUBSTITUTED 1,2,3-TRIAZOLES NOVO NORDISK A/S (DK) 1997-10-30 WO disclosed
US-5679643-A USUFUL AS CHROMATOGRAPHIC AFFINITY LIGANDS, BINDING REAGENTS, AND ENZYME INHIBITOR TERRAPIN TECHNOLOGIES, INC. (US) 1997-10-21 US disclosed
US-5599903-A TRIPEPTIDE; LIGAND, ENZYME INHIBITOR TERRAPIN TECHNOLOGIES, INC. (US) 1997-02-04 US disclosed
EP-0720620-A1 GLUTATHIONE ANALOGS AND PARALOG PANELS COMPRISING GLUTATHIONE MIMICS TERRAPIN TECHNOLOGIES, INC. (US) 1996-07-10 EP disclosed
WO-1995008563-A1 GLUTATHIONE ANALOGS AND PARALOG PANELS COMPRISING GLUTATHIONE MIMICS TERRAPIN TECHNOLOGIES, INC. (US) 1995-03-30 WO disclosed
EP-0645397-A1 Glutathione analogs and paralog panels comprising glutathione mimics TERRAPIN TECHNOLOGIES, INC. (US) 1995-03-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022142-A1 MACROCYCLIC IMMUNOMODULATORS CD274, PDCD1LG2, PDCD1 KMT2A 1052/4885FABP5 2537/4885FABP7 2103/4885
US-20260124312-A1 BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR EPHA2 EPHA2, EPHB2, ERBB2 KMT2A 1304/4885FABP5 2727/4885FABP7 1978/4885
US-20260036595-A1 STRUCTURE-BASED PEPTIDES FOR DETECTION OF TRANSTHYRETIN AMYLOID FIBRILS AND AGGREGATES IN PREECLAMPSIA TTR, APP, SERPINA3 KMT2A 4282/4885FABP5 115/4885FABP7 50/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.