Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.55 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | SLC26A3 | P40879 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12155348 | 0.79 | MAOB (0.53) | MAOBANO1MAOASLC26A3NR4A2 | |
| SCHEMBL12155353 | 0.78 | MAOB (0.64) | MAOBMAOASLC26A3ACHECYP19A1 | |
| SCHEMBL28085657 | 0.77 | MAOB (0.52) | MAOBABCG2CA1CA2POLB | |
| SCHEMBL28143005 | 0.76 | MAOB (0.72) | MAOBABCG2CA1CA2 | |
| SCHEMBL12172454 | 0.74 | MAOB (0.49) | MAOBANO1MAOASLC26A3NR4A2 | |
| SCHEMBL28085658 | 0.72 | MAOB (0.54) | MAOBABCG2CA1CA2POLB | |
| SCHEMBL5617559 | 0.71 | MAOB (1.00) | MAOBMAOAACHE | |
| SCHEMBL7463411 | 0.69 | MAOB (0.72) | MAOBABCG2CA1CA2 | |
| SCHEMBL7117054 | 0.69 | MAOB (0.72) | MAOBMAOAABCG2CA1CA2 | |
| SCHEMBL31511409 | 0.69 | MAOB (0.72) | MAOBABCG2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048889-B2 | 3,4-disubstituted coumarin and quinolone compounds | XTL BIOPHARMACEUTICALS LTD. (IL) | 2011-11-01 | — | — | US | disclosed |
| US-8048889-B2 | 3,4-disubstituted coumarin and quinolone compounds | XTL BIOPHARMACEUTICALS LTD. (IL) | 2011-11-01 | — | — | US | disclosed |