Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL29678 | 1.00 | — | — | |
| Bicarbonate SCHEMBL6523382 | 0.94 | — | — | |
| Bicarbonate SCHEMBL11293720 | 0.94 | — | — | |
| Bicarbonate SCHEMBL11420335 | 0.94 | — | — | |
| Bicarbonate SCHEMBL17685557 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL8038418 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL8679043 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL21680141 | 0.94 | — | — | |
| Bicarbonate SCHEMBL21059504 | 0.94 | CA4 (0.46) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL16653582 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8500849-B2 | Reactive gas detection in complex backgrounds | SPECTRASENSORS, INC. (US) | 2013-08-06 | — | — | US | claimed |
| US-20120185179-A1 | REACTIVE GAS DETECTION IN COMPLEX BACKGROUNDS | ENDRESS+HAUSER OPTICAL ANALYSIS, INC. | 2012-07-19 | — | — | US | claimed |
| US-8152900-B2 | Reactive gas detection in complex backgrounds | SPECTRASENSORS, INC. (US) | 2012-04-10 | — | — | US | claimed |
| US-20110093215-A1 | Reactive Gas Detection In Complex Backgrounds | ENDRESS+HAUSER OPTICAL ANALYSIS, INC. | 2011-04-21 | — | — | US | claimed |
| US-7819946-B2 | Reactive gas detection in complex backgrounds | SPECTRASENSORS, INC. (US) | 2010-10-26 | — | — | US | claimed |
| US-20100201989-A1 | Reactive Gas Detection In Complex Backgrounds | ENDRESS+HAUSER OPTICAL ANALYSIS, INC. | 2010-08-12 | — | — | US | claimed |
| US-7704301-B2 | Reactive gas detection in complex backgrounds | SPECTRASENSORS, INC. (US) | 2010-04-27 | — | — | US | claimed |
| EP-2140246-A1 | REACTIVE GAS DETECTION IN COMPLEX BACKGROUNDS | SpectraSensors, Inc. (US) | 2010-01-06 | — | — | EP | claimed |
| WO-2008128114-A1 | REACTIVE GAS DETECTION IN COMPLEX BACKGROUNDS | SPECTRASENSORS, INC. (US) | 2008-10-23 | — | — | WO | claimed |
| US-20080255769-A1 | Reactive Gas Detection In Complex Backgrounds | ENDRESS+HAUSER OPTICAL ANALYSIS, INC. | 2008-10-16 | — | — | US | claimed |
| US-20240376257-A1 | POLY(GLYCOLIC ACID) FOR CONTAINERS AND FILMS WITH REDUCED GAS PERMEABILITY | DAK AMERICAS LLC (US) | 2024-11-14 | — | — | US | disclosed |
| US-12065538-B2 | Poly(glycolic acid) for containers and films with reduced gas permeability | DAK AMERICAS LLC (US) | 2024-08-20 | — | — | US | disclosed |
| US-20230323020-A1 | POLY(GLYCOLIC ACID) FOR CONTAINERS AND FILMS WITH REDUCED GAS PERMEABILITY | DAK AMERICAS LLC | 2023-10-12 | — | — | US | disclosed |
| US-11548979-B2 | Poly(glycolic acid) for containers and films with reduced gas permeability | DAK AMERICAS LLC (US) | 2023-01-10 | — | — | US | disclosed |
| US-11155677-B2 | Process for making poly(glycolic acid) for containers and films with reduced gas permeability | DAK AMERICAS LLC (US) | 2021-10-26 | — | — | US | disclosed |
| US-20100201989-A1 | Reactive Gas Detection In Complex Backgrounds | ENDRESS+HAUSER OPTICAL ANALYSIS, INC. | 2010-08-12 | — | — | US | disclosed |
| US-7704301-B2 | Reactive gas detection in complex backgrounds | SPECTRASENSORS, INC. (US) | 2010-04-27 | — | — | US | disclosed |
| EP-2140246-A1 | REACTIVE GAS DETECTION IN COMPLEX BACKGROUNDS | SpectraSensors, Inc. (US) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008128114-A1 | REACTIVE GAS DETECTION IN COMPLEX BACKGROUNDS | SPECTRASENSORS, INC. (US) | 2008-10-23 | — | — | WO | disclosed |
| US-20080255769-A1 | Reactive Gas Detection In Complex Backgrounds | ENDRESS+HAUSER OPTICAL ANALYSIS, INC. | 2008-10-16 | — | — | US | disclosed |