Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 12/20 | 0.36 |
| ▸ | ITGAV | P06756 | 12/20 | 0.36 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 5/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.32 |
| ▸ | ITGB6 | P18564 | 2/20 | 0.32 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL325029 | 0.83 | ITGB3 (0.39) | ITGB3ITGAVCXCR4ITGA2BNNMT | |
| SCHEMBL16607409 | 0.83 | ITGB3 (0.36) | ITGB3ITGAVUHRF1CXCR4ITGA2B | |
| SCHEMBL20091210 | 0.80 | UHRF1 (0.36) | ITGB3ITGAVUHRF1CXCR4ITGA2B | |
| SCHEMBL325441 | 0.79 | NPC1 (0.39) | ITGB3ITGAVCXCR4ITGA2BNNMT | |
| SCHEMBL325440 | 0.79 | NPC1 (0.39) | ITGB3ITGAVCXCR4ITGA2BNNMT | |
| SCHEMBL10258928 | 0.79 | NPC1 (0.39) | ITGB3ITGAVCXCR4ITGA2BNNMT | |
| SCHEMBL279665 | 0.77 | UHRF1 (0.53) | ITGB3ITGAVUHRF1CXCR4ITGA2B | |
| SCHEMBL30474583 | 0.77 | UHRF1 (0.53) | ITGB3ITGAVUHRF1CXCR4ITGA2B | |
| SCHEMBL18105218 | 0.76 | ITGB3 (0.33) | ITGB3ITGAVUHRF1CXCR4ITGA2B | |
| SCHEMBL21329809 | 0.76 | ITGAV (0.36) | ITGB3ITGAVCXCR4ITGA2BITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385042-A1 | Prokineticin 1 receptor antagonists | Janssen Pharmaceutica N.V. (BE) | 2011-11-09 | — | — | EP | disclosed |