SCHEMBL1216

SCHEMBL1216

Fc1ccc(I)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18472615 1.00
Phosphine SCHEMBL28954456 0.96
Bromide SCHEMBL9419856 0.96
SCHEMBL7216161 0.96
SCHEMBL3782362 0.90 APP (0.46)
SCHEMBL13149702 0.83 APP (0.42)
SCHEMBL21401645 0.83 APP (0.42)
SCHEMBL9440388 0.83 MEN1 (0.44)
SCHEMBL13149658 0.83 APP (0.42)
SCHEMBL9440312 0.83 APP (0.57)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3381 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121574107-A Method for synthesizing aryl thiobenzothiazole compound based on cuprous chloride 苏州大学 2026-02-27 CN claimed
US-20250309354-A1 ELECTROLYTE COMPRISING AROMATIC COMPOUND WITH NON-FLUORINE HALOGEN SUBSTITUTE AND BATTERIES COMPRISING SAME FACTORIAL INC. 2025-10-02 US claimed
CN-119932584-A Method for synthesizing 1, 1-diaryl compound by using non-activated olefin 哈尔滨工业大学(深圳)(哈尔滨工业大学深圳科技创新研究院) 2025-05-06 CN claimed
CN-119932587-A Synthesis method of pimozide intermediate 哈尔滨工业大学(深圳)(哈尔滨工业大学深圳科技创新研究院) 2025-05-06 CN claimed
CN-119346167-A Catalytic system and method for synthesizing diaryl acetylene from calcium carbide and iodo aromatic hydrocarbon 石河子大学 2025-01-24 CN claimed
CN-116178092-B Preparation method of 1, 4-tetraphenyl-1, 3-butadiene and derivatives thereof 苏州大学 2024-11-22 CN claimed
CN-118530173-A Palladium-catalyzed quinoline and method for selectively arylating C (8) -H bond of derivative thereof 洛阳理工学院 2024-08-23 CN claimed
CN-118287149-A Preparation method and application of palladium-loaded lignin catalyst 东北林业大学 2024-07-05 CN claimed
CN-114181048-B Preparation method of high-yield 4-fluorobiphenol 宁夏清研高分子新材料有限公司 2024-06-21 CN claimed
CN-117895068-A Solid electrolyte, preparation method thereof and solid lithium battery 武汉中原长江科技发展有限公司 2024-04-16 CN claimed
CN-1504470-A 3,5-difluoro-4-cyan benzene boric acid ester compound, preparing process thereof and application in liquid crystal composition 石家庄实力克液晶材料有限公司 2004-06-16 CN claimed
US-20030216598-A1 Method for producing tetrakis ( fluoroaryl) borate-magnesium compound NIPPON SHOKUBAI CO., LTD. (JP) 2003-11-20 US claimed
EP-1362860-A1 Method for producing tetrakis (fluoroaryl) borate magnesium compound Nippon Shokubai Co., Ltd. (JP) 2003-11-19 EP claimed
WO-2003080597-A1 METHOD FOR MANUFACTURE OF SERTINDOLE H. LUNDBECK A/S (DK) 2003-10-02 WO claimed
EP-0635008-B1 PIPERAZIDES OF SUBSTITUTED PHENYLALANINE DERIVATES AS THROMBIN INHIBITORS PENTAPHARM AG (CH) 2002-09-04 EP claimed
EP-1068255-A2 POLY(ARYLENE ETHER) COMPOSITIONS AND METHODS OF MANUFACTURE THEREOF AlliedSignal Inc. (US) 2001-01-17 EP claimed
US-6124421-A A SEMICONDUCTOR DEVICE COMPRISING A DIELECTRIC LAYER DISPOSED OVERLYING A SURFACE, COMPRISES A POLY(ARYLENE ETHER) ALLIEDSIGNAL INC. (US) 2000-09-26 US claimed
WO-1999029761-A2 POLY(ARYLENE ETHER) COMPOSITIONS AND METHODS OF MANUFACTURE THEREOF ALLIEDSIGNAL INC. (US) 1999-06-17 WO claimed
US-4956507-A GRIGNARD REAGENTS FROM P-HALOFLUOROBENZENE AND MAGNESIUM COUPLING TO FORM P,P*-DIFLUOROBIPHENYL PHILLIPS PETROLEUM COMPANY (US) 1990-09-11 US claimed
US-4716254-A CATALYTIC IODINATION OF HALOBENZENE PHILLIPS PETROLEUM COMPANY (US) 1987-12-29 US claimed