SCHEMBL13149702

SCHEMBL13149702

Fc1ccc(C(c2ccc(I)cc2)(c2ccc(I)cc2)c2ccc(I)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.42
KCNN4 O15554 3/20 0.38
RAB9A P51151 2/20 0.37
USP2 O75604 1/20 0.37
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
NPC1 O15118 1/20 0.35
MAPT P10636 1/20 0.35
XBP1 P17861 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CYP19A1 P11511 2/20 0.34
TRPV1 Q8NER1 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
ACHE P22303 1/20 0.33
MAPK13 O15264 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13149658 1.00 APP (0.42) APPKCNN4RAB9AUSP2MEN1
SCHEMBL16361071 0.86 KCNN4 (0.46) KCNN4RAB9AUSP2MEN1KMT2A
SCHEMBL1986810 0.86 APP (0.40) APPTRPV1CA1CA2CYP3A4
SCHEMBL28553350 0.86 APP (0.40) APPTRPV1CA1CA2CYP3A4
SCHEMBL18472615 0.83
SCHEMBL1216 0.83
SCHEMBL9440519 0.82 APP (0.41) APPKCNN4RAB9AUSP2MEN1
SCHEMBL7216161 0.80
Bromide SCHEMBL9419856 0.80
Phosphine SCHEMBL28954456 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7799949-B2 Tetraphenylmethane skeleton-containing compound FUJIFILM CORPORATION (JP) 2010-09-21 US disclosed
US-7799949-B2 Tetraphenylmethane skeleton-containing compound FUJIFILM CORPORATION (JP) 2010-09-21 US disclosed
US-20090227812-A1 TETRAPHENYLMETHANE SKELETON-CONTAINING COMPOUND FUJIFILM CORPORATION (JP) 2009-09-10 US disclosed
US-20090227812-A1 TETRAPHENYLMETHANE SKELETON-CONTAINING COMPOUND FUJIFILM CORPORATION (JP) 2009-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090227812-A1 TETRAPHENYLMETHANE SKELETON-CONTAINING COMPOUND PAH, TSNAX, ZFX APP 971/4885KCNN4 3336/4885RAB9A 2377/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.