Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSPO | P30536 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1896211 | 0.91 | HSD17B10 (0.45) | HSD17B10ELANEALDH1A1KDM4EGLA | |
| SCHEMBL12166073 | 0.89 | ALDH1A1 (0.50) | HSD17B10ALDH1A1KDM4EGLAGAA | |
| SCHEMBL12166067 | 0.88 | MYC (0.45) | HSD17B10ELANEALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL12166061 | 0.87 | MYC (0.46) | HSD17B10ELANEALDH1A1KDM4EGLA | |
| SCHEMBL11926707 | 0.86 | MYC (0.52) | ELANEALDH1A1GAATSPOL3MBTL1 | |
| SCHEMBL31179907 | 0.82 | MYC (0.56) | ELANEALDH1A1KDM4EGAAL3MBTL1 | |
| SCHEMBL12282047 | 0.80 | NR4A2 (0.48) | ELANEALDH1A1KDM4EGAANR4A2 | |
| SCHEMBL1893720 | 0.80 | NR4A2 (0.48) | ALDH1A1KDM4EGLAGAANR4A2 | |
| SCHEMBL12166116 | 0.79 | HSD17B10 (0.44) | HSD17B10ELANEKDM4EGAAL3MBTL1 | |
| SCHEMBL12100556 | 0.79 | MYC (0.52) | HSD17B10ALDH1A1KDM4EGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012599-B2 | Nitrogen-containing condensed heterocyclic compounds for OLEDs | MERCK PATENT GMBH (DE) | 2015-04-21 | — | — | US | disclosed |
| US-9012599-B2 | Nitrogen-containing condensed heterocyclic compounds for OLEDs | MERCK PATENT GMBH (DE) | 2015-04-21 | — | — | US | disclosed |
| US-20120232241-A1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUNDS FOR OLEDS | MERCK PATENT GMBH PATENTS & SCIENTIFIC INFORMATION (DE) | 2012-09-13 | — | — | US | disclosed |
| US-20120232241-A1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUNDS FOR OLEDS | MERCK PATENT GMBH PATENTS & SCIENTIFIC INFORMATION (DE) | 2012-09-13 | — | — | US | disclosed |
| WO-2011060867-A1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUNDS FOR OLEDS | MERCK PATENT GMBH (DE) | 2011-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120232241-A1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUNDS FOR OLEDS | OCIAD2, OCIAD1, ODC1 | HSD17B10 1075/4885ELANE 1096/4885ALDH1A1 1351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.