SCHEMBL12166274

SCHEMBL12166274

Cc1nc(-c2cccc(-c3ccccc3)c2)nc(-c2cc(-c3ccccc3)cc(-c3ccccc3)c2)n1

nearest known ligand 0.67

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.67
GP6 Q9HCN6 1/20 0.44
LMNA P02545 2/20 0.42
RAB9A P51151 1/20 0.42
KMO O15229 1/20 0.41
KDM4E B2RXH2 1/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
KMT2A Q03164 1/20 0.41
NR1I3 Q14994 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12166279 0.98 L3MBTL1 (0.69) L3MBTL1GP6LMNARAB9AKMO
SCHEMBL22448042 0.96 L3MBTL1 (0.73) L3MBTL1GP6LMNARAB9AKMO
SCHEMBL19295114 0.96 L3MBTL1 (0.72) L3MBTL1GP6LMNARAB9AKMO
SCHEMBL11978721 0.96 L3MBTL1 (0.72) L3MBTL1GP6LMNARAB9AKMO
SCHEMBL19295116 0.96 L3MBTL1 (0.72) L3MBTL1GP6LMNARAB9AKMO
SCHEMBL12166266 0.94 L3MBTL1 (0.76) L3MBTL1GP6LMNARAB9AKMO
SCHEMBL19501122 0.94 L3MBTL1 (0.76) L3MBTL1GP6LMNARAB9AKMO
SCHEMBL10052454 0.94 L3MBTL1 (0.75) L3MBTL1LMNARAB9AKDM4EMEN1
SCHEMBL23008315 0.92 L3MBTL1 (0.73) L3MBTL1GP6LMNARAB9AKMO
SCHEMBL16919887 0.92 L3MBTL1 (0.73) L3MBTL1GP6LMNARAB9AKMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11760734-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-09-19 US disclosed
US-11760734-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-09-19 US disclosed
US-20210221775-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-07-22 US disclosed
US-10981880-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2021-04-20 US disclosed
US-20190169139-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-06-06 US disclosed
US-10233159-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2019-03-19 US disclosed
US-20160096809-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2016-04-07 US disclosed
US-20160096809-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2016-04-07 US disclosed
US-9187456-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2015-11-17 US disclosed
US-9187456-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2015-11-17 US disclosed
US-20120228554-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-09-13 US disclosed
US-20120228554-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-09-13 US disclosed
WO-2011060859-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2011-05-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10233159-B2 Materials for organic electroluminescent devices SLCO4C1, SLCO2B1, SLCO2A1 L3MBTL1 2132/4885GP6 773/4885LMNA 1143/4885
US-20190169139-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SLCO4C1, SLCO2B1, SLCO2A1 L3MBTL1 2132/4885GP6 773/4885LMNA 1143/4885
US-20210221775-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SLCO4C1, SLCO2B1, SLCO2A1 L3MBTL1 2132/4885GP6 773/4885LMNA 1143/4885
US-10981880-B2 Materials for organic electroluminescent devices SLCO4C1, SLCO2B1, SLCO2A1 L3MBTL1 2132/4885GP6 773/4885LMNA 1143/4885
US-20120228554-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SLCO4C1, SLCO2B1, SLCO2A1 L3MBTL1 2132/4885GP6 773/4885LMNA 1143/4885
US-20160096809-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SLCO4C1, SLCO2B1, SLCO2A1 L3MBTL1 2132/4885GP6 773/4885LMNA 1143/4885
US-11760734-B2 Materials for organic electroluminescent devices SLCO4C1, SLCO2B1, SLCO2A1 L3MBTL1 2132/4885GP6 773/4885LMNA 1143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.