Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14713311 | 0.76 | SLC6A4 (0.46) | KMT2ASIGMAR1KDM1ASMN1; SMN2SLC6A4 | |
| Hydrochloric Acid SCHEMBL2586633 | 0.75 | HRH3 (0.45) | SIGMAR1KDM1ASLC6A4 | |
| SCHEMBL12175496 | 0.72 | SIGMAR1 (0.50) | DRD2KMT2AALDH1A1SIGMAR1SLC6A4 | |
| Hydrochloric Acid SCHEMBL2583839 | 0.72 | SIGMAR1 (0.49) | DRD2KMT2AALDH1A1SIGMAR1 | |
| SCHEMBL8395907 | 0.68 | KCNH2 (0.43) | DRD2KCNH2KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL11246210 | 0.68 | SLC6A4 (0.58) | DRD2KMT2ASMN1; SMN2SLC6A4 | |
| SCHEMBL11258195 | 0.67 | SLC6A4 (0.61) | DRD2SIGMAR1SLC6A4 | |
| SCHEMBL11191207 | 0.67 | SLC6A4 (0.62) | DRD2KCNH2SLC6A4 | |
| Bromide SCHEMBL11265180 | 0.67 | SLC6A4 (0.60) | DRD2SIGMAR1SLC6A4 | |
| SCHEMBL11191206 | 0.67 | SLC6A4 (0.62) | DRD2KCNH2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011137331-A2 | 4-FLUORO-4-ARYLPIPERDIN-1-YL DERIVATIVES AS MU OPIOID FUNCTION MODERATORS | KINENTIA BIOSCIENCES LLC (US) | 2011-11-03 | — | — | WO | disclosed |