Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.57 |
| ▸ | LIPE | Q05469 | 10/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1590437 | 0.86 | EGLN1 (0.56) | EGLN1LIPEITGB3ITGA2B | |
| SCHEMBL743526 | 0.85 | EGLN1 (0.55) | EGLN1LIPEITGB3ITGA2BMGLL | |
| SCHEMBL1589368 | 0.84 | EGLN1 (0.54) | EGLN1LIPE | |
| SCHEMBL5592 | 0.84 | EGLN1 (0.54) | EGLN1LIPEITGB3ITGA2BMGLL | |
| SCHEMBL9870 | 0.84 | EGLN1 (0.54) | EGLN1LIPE | |
| SCHEMBL9871 | 0.84 | EGLN1 (0.54) | EGLN1LIPE | |
| SCHEMBL25676822 | 0.83 | EGLN1 (0.52) | EGLN1LIPEMGLL | |
| SCHEMBL759281 | 0.83 | EGLN1 (0.53) | EGLN1LIPEITGB3ITGA2B | |
| SCHEMBL10330 | 0.82 | LIPE (0.56) | EGLN1LIPEITGB3ITGA2B | |
| SCHEMBL10331 | 0.82 | LIPE (0.56) | EGLN1LIPEITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011045292-A1 | SPIRO-CONDENSED CYCLOHEXANE DERIVATIVES AS HSL INHIBITORS USEFUL FOR THE TREATMENT OF DIABETES | F. HOFFMANN-LA ROCHE AG (CH) | 2011-04-21 | — | — | WO | disclosed |