Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 9/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | NSD2 | O96028 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | AURKA | O14965 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.52 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177594 | 0.95 | PSMB8 (0.70) | PSMB8ALDH1A1POLBMAPTLMNA | |
| SCHEMBL12177782 | 0.92 | PSMB8 (0.82) | PSMB8ALDH1A1POLBMAPTLMNA | |
| SCHEMBL12177429 | 0.91 | PSMB8 (0.65) | PSMB8ALDH1A1POLBMAPTLMNA | |
| SCHEMBL12177187 | 0.91 | PSMB8 (0.80) | PSMB8ALDH1A1POLBMAPTLMNA | |
| SCHEMBL12177768 | 0.89 | PSMB8 (0.84) | PSMB8ALDH1A1POLBMAPTTDP1 | |
| SCHEMBL12177333 | 0.88 | PSMB8 (0.62) | PSMB8ALDH1A1POLBMAPTLMNA | |
| SCHEMBL12177213 | 0.88 | PSMB8 (0.75) | PSMB8ALDH1A1POLBMAPTLMNA | |
| SCHEMBL12177746 | 0.86 | PSMB8 (0.73) | PSMB8ALDH1A1POLBMAPTLMNA | |
| SCHEMBL12177176 | 0.85 | PSMB8 (0.71) | PSMB8ALDH1A1POLBMAPTLMNA | |
| SCHEMBL14426566 | 0.84 | POLB (0.69) | PSMB8ALDH1A1POLBMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |