Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 8/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MGAM | O43451 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12177594 | 0.96 | PSMB8 (0.70) | PSMB8KMT2AALDH1A1POLBMAPT | |
| SCHEMBL12177176 | 0.95 | PSMB8 (0.71) | PSMB8KMT2AALDH1A1POLBMAPT | |
| SCHEMBL12177593 | 0.91 | PSMB8 (0.78) | PSMB8KMT2AALDH1A1POLBMAPT | |
| SCHEMBL12177746 | 0.90 | PSMB8 (0.73) | PSMB8KMT2AALDH1A1POLBMAPT | |
| SCHEMBL12177187 | 0.90 | PSMB8 (0.80) | PSMB8KMT2AALDH1A1POLBMAPT | |
| SCHEMBL12177333 | 0.89 | PSMB8 (0.62) | PSMB8KMT2AALDH1A1POLBMAPT | |
| SCHEMBL12177768 | 0.88 | PSMB8 (0.84) | PSMB8KMT2AALDH1A1POLBMAPT | |
| SCHEMBL12177563 | 0.88 | PSMB8 (0.63) | PSMB8KMT2AALDH1A1POLBMAPT | |
| SCHEMBL12177564 | 0.83 | PSMB8 (0.67) | PSMB8KMT2AALDH1A1POLBMAPT | |
| SCHEMBL14426566 | 0.83 | POLB (0.69) | PSMB8KMT2AALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011135303-A2 | UBIQUITINATION MODULATORS | ITI SCOTLAND LIMITED (GB) | 2011-11-03 | — | — | WO | disclosed |