SCHEMBL12184428

SCHEMBL12184428

CCOC(=O)c1ncc(CCl)s1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 2/20 0.45
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ CDC7 O00311 2/20 0.42
▸ DBF4 Q9UBU7 2/20 0.42
▸ ALDH1A1 P00352 4/20 0.40
▸ GAA P10253 3/20 0.40
▸ HPGD P15428 3/20 0.40
▸ MAPK1 P28482 2/20 0.40
▸ MAPT P10636 2/20 0.40
▸ GABRP O00591 1/20 0.39
▸ GABRD O14764 1/20 0.39
▸ GABRA1 P14867 1/20 0.39
▸ GABRB1 P18505 1/20 0.39
▸ GABRG2 P18507 1/20 0.39
▸ GABRB3 P28472 1/20 0.39
▸ GABRA5 P31644 1/20 0.39
▸ GABRA3 P34903 1/20 0.39
▸ GABRA2 P47869 1/20 0.39
▸ GABRB2 P47870 1/20 0.39
▸ GABRA4 P48169 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5326662 0.85 SMN1; SMN2 (0.46) SMN1; SMN2CDC7DBF4ALDH1A1GAA
SCHEMBL12184418 0.83 SMN1; SMN2 (0.49) SMN1; SMN2CDC7DBF4ALDH1A1GAA
SCHEMBL1806521 0.83 SMN1; SMN2 (0.45) SMN1; SMN2CDC7DBF4ALDH1A1GAA
SCHEMBL131458 0.83 CDC7 (0.46) SMN1; SMN2CDC7DBF4ALDH1A1GAA
SCHEMBL3426226 0.80 CCNE1 (0.45) SMN1; SMN2CDC7DBF4GAAMAPK1
SCHEMBL128677 0.79 CDC7 (0.46) SMN1; SMN2CDC7DBF4ALDH1A1GAA
SCHEMBL16933028 0.77 CDC7 (0.60) SMN1; SMN2CDC7DBF4ALDH1A1GAA
SCHEMBL19224496 0.77 LMNA (0.50) SMN1; SMN2CDC7DBF4ALDH1A1MAPK1
SCHEMBL30836778 0.76 PDCD1 (0.42) SMN1; SMN2CDC7DBF4ALDH1A1GAA
SCHEMBL17967261 0.76 SMN1; SMN2 (0.48) SMN1; SMN2L3MBTL1CDC7DBF4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2952096-B1 Amide compound, an arthropod pest control agent and a method for controlling arthropod pest SUMITOMO CHEMICAL CO (JP) 2018-04-04 — — EP disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 — — US disclosed
EP-2952096-A1 METHOD FOR CONTROLLING ARTHROPOD PEST Sumitomo Chemical Company, Limited (JP) 2015-12-09 — — EP disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 — — US disclosed
WO-2011142359-A1 SPIRO COMPOUND AND DRUG FOR ACTIVATING ADIPONECTIN RECEPTOR 日産化学工業株式会社 (JP) 2011-11-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST H1-0, H1-3, H1-2 SMN1; SMN2 2187/4885L3MBTL1 369/4885CDC7 3905/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback