Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 11/20 | 0.54 |
| ▸ | PLAT | P00750 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14749308 | 1.00 | PRCP (0.54) | PRCPPLATL3MBTL1NPC1CYP1A2 | |
| SCHEMBL12184580 | 0.91 | PRCP (0.56) | PRCPL3MBTL1NPC1CYP1A2CYP2C9 | |
| SCHEMBL2598787 | 0.91 | PRCP (0.56) | PRCPL3MBTL1NPC1CYP1A2CYP2C9 | |
| SCHEMBL14749291 | 0.90 | PRCP (0.46) | PRCPL3MBTL1NPC1CYP1A2CYP3A4 | |
| SCHEMBL14737307 | 0.84 | PRCP (0.56) | PRCP | |
| SCHEMBL12183895 | 0.84 | PRCP (0.56) | PRCP | |
| SCHEMBL2599453 | 0.79 | PRCP (0.51) | PRCPPLATKCNH2 | |
| SCHEMBL14686475 | 0.78 | PRCP (0.56) | PRCPPLAT | |
| SCHEMBL12184145 | 0.78 | PRCP (0.52) | PRCPPLAT | |
| SCHEMBL14737395 | 0.77 | PRCP (0.56) | PRCPL3MBTL1NPC1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011146354-A1 | NOVEL PROLYLCARBOXYPEPTIDASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2011-11-24 | — | — | WO | disclosed |