Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 12/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12183895 | 1.00 | PRCP (0.56) | PRCPDRD2DRD4DRD3CYP11B1 | |
| SCHEMBL14749289 | 0.91 | PRCP (0.56) | PRCPDRD2DRD4DRD3 | |
| SCHEMBL12184727 | 0.84 | PRCP (0.54) | PRCP | |
| SCHEMBL14749308 | 0.84 | PRCP (0.54) | PRCP | |
| SCHEMBL14686540 | 0.81 | PRCP (0.83) | PRCPDRD2DRD4DRD3 | |
| SCHEMBL14737198 | 0.79 | PRCP (0.55) | PRCP | |
| SCHEMBL14749368 | 0.79 | PRCP (0.67) | PRCPDRD2DRD3 | |
| SCHEMBL14749369 | 0.76 | PRCP (0.59) | PRCPDRD2DRD4DRD3 | |
| SCHEMBL14736790 | 0.76 | PRCP (0.58) | PRCPDRD2DRD4DRD3 | |
| SCHEMBL12184022 | 0.76 | PRCP (0.58) | PRCPDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130059830-A1 | NOVEL PROLYLCARBOXYPEPTIDASE INHIBITORS | MERCK SHARP & DOHME CORP | 2013-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130059830-A1 | NOVEL PROLYLCARBOXYPEPTIDASE INHIBITORS | PRCP, PREP, ENPEP | PRCP 1/4885DRD2 4864/4885DRD4 4740/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.