⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12176034 | 1.00 | — | — | |
| SCHEMBL11068641 | 0.75 | — | — | |
| SCHEMBL16945607 | 0.75 | — | — | |
| SCHEMBL24473931 | 0.74 | — | — | |
| SCHEMBL15937094 | 0.74 | — | — | |
| SCHEMBL20322830 | 0.74 | — | — | |
| SCHEMBL685471 | 0.73 | — | — | |
| SCHEMBL151855 | 0.73 | — | — | |
| Bromide SCHEMBL11092910 | 0.72 | — | — | |
| SCHEMBL8283923 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3293175-B1 | METHODS FOR PURIFICATION OF SERINE PROTEASES | ALEXION PHARMA INC (US) | 2021-12-01 | — | — | EP | disclosed |
| EP-2569324-B1 | AMINOGLYCOSIDE DERIVATIVES | REMPEX PHARMACEUTICALS INC (US) | 2017-12-06 | — | — | EP | disclosed |
| US-8906868-B2 | Aminoglycoside derivatives | REMPEX PHARMACEUTICALS, INC. (US) | 2014-12-09 | — | — | US | disclosed |
| WO-2011143497-A1 | AMINOGLYCOSIDE DERIVATIVES | REMPEX PHARMACEUTICALS, INC. (US) | 2011-11-17 | — | — | WO | disclosed |
| US-20090318437-A1 | SUBSTITUTED PYRAZOLO[1,5-a] PYRIDINE COMPOUNDS AND THEIR METHODS OF USE | MEDICINOVA, INC. | 2009-12-24 | — | — | US | disclosed |