⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL8449744 | 0.95 | — | — | |
| Propane SCHEMBL28618954 | 0.88 | — | — | |
| SCHEMBL17236155 | 0.76 | — | — | |
| SCHEMBL12187169 | 0.76 | — | — | |
| SCHEMBL12176034 | 0.73 | — | — | |
| SCHEMBL12187331 | 0.73 | — | — | |
| SCHEMBL8544077 | 0.73 | — | — | |
| SCHEMBL13760484 | 0.73 | — | — | |
| SCHEMBL19672413 | 0.70 | — | — | |
| SCHEMBL23250589 | 0.70 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813302-A | Substituted tetrahydrofuran-2-carboxamides as sodium channel modulators | 沃泰克斯药物股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| US-20230141913-A2 | PHENOXY(HETERO)ARYL ETHERS OF ANTIPROLIFERACTIVE ACTIVITY | Xeniopro GmbH (DE) | 2023-05-11 | — | — | US | disclosed |
| EP-3533795-A1 | NOVEL PYRIMIDINE DERIVATIVE HAVING ANTIMALARIAL ACTIVITY | Carna Biosciences Inc. (JP) | 2019-09-04 | — | — | EP | disclosed |
| US-9981070-B2 | Coating composition and medical device | TERUMO KABUSHIKI KAISHA (JP) | 2018-05-29 | — | — | US | disclosed |
| US-20180072726-A9 | NOVEL AZA-OXO-INDOLES FOR THE TREATMENT AND PROPHYLAXIS OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | HOFFMANN-LA ROCHE INC. (US) | 2018-03-15 | — | — | US | disclosed |
| US-20180000791-A1 | METHODS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH ANGIOGENESIS USING A VASCULAR ADHESION PROTEIN-1 (VAP-1) INHIBITOR | MASSACHUSETTS EYE & EAR INFIRMARY (US) | 2018-01-04 | — | — | US | disclosed |
| US-9783490-B2 | Antimicrobial compounds, their synthesis and applications thereof | THE SECRETARY OF STATE FOR HEALTH (GB) | 2017-10-10 | — | — | US | disclosed |
| WO-2017161344-A1 | COMPOSITIONS AND METHODS FOR TREATING PARASITIC DISEASES | THE REGANTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-09-21 | — | — | WO | disclosed |
| US-20170266326-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2017-09-21 | — | — | US | disclosed |
| US-20170174620-A1 | LINKED DIARYL COMPOUNDS WITH ANTICANCER PROPERTIES AND METHODS OF USING THE SAME | UNIVERSITY OF MARYLAND, COLLEGE PARK | 2017-06-22 | — | — | US | disclosed |
| US-20090054488-A1 | Isomigrastatin Analogs In The Treatment Of Cancer | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-02-26 | — | — | US | disclosed |
| WO-2008061616-A1 | PROCESS FOR PREPARING 2-AMINOOXYETHANOL | BAYER CROPSCIENCE AG (DE) | 2008-05-29 | — | — | WO | disclosed |
| EP-1925610-A1 | Production process of 2-aminooxyethanol | Bayer CropScience AG (DE) | 2008-05-28 | — | — | EP | disclosed |
| WO-2008010921-A2 | MODULATORS OF PHARMACOKINETIC PROPERTIES OF THERAPEUTICS | GILEAD SCIENCES, INC. (US) | 2008-01-24 | — | — | WO | disclosed |
| US-20070060575-A1 | Aspartyl protease inhibitors | MERCK SHARP & DOHME LLC | 2007-03-15 | — | — | US | disclosed |
| US-20070037852-A1 | Migrastatin analogs and uses thereof | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2007-02-15 | — | — | US | disclosed |
| US-20070037783-A1 | Migrastatin analogs and uses thereof | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2007-02-15 | — | — | US | disclosed |
| CN-1105706-C | Cyclic amidino formulations useful as nitric oxide synthase inhibitors | SEARLE & CO (US) | 2003-04-16 | — | — | CN | disclosed |
| CN-1305993-A | Cyclic guanyl preparation used as nitrogen oxide synthetic enzyme inhibitor | SEARLE & CO (US) | 2001-08-01 | — | — | CN | disclosed |
| CN-1189823-A | Cyclic amidino formulations useful as nitric oxide synthase inhibitors | SEARLE & CO (US) | 1998-08-05 | — | — | CN | disclosed |