SCHEMBL12189673

SCHEMBL12189673

O=C(O)CNC(=O)CCCCCCO

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.71
GPR84 Q9NQS5 1/20 0.56
FFAR1 O14842 1/20 0.56
FFAR4 Q5NUL3 1/20 0.56
FAAH O00519 6/20 0.54
FNTA P49354 1/20 0.53
FNTB P49356 1/20 0.53
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
RECQL P46063 2/20 0.47
KDM4E B2RXH2 1/20 0.46
USP2 O75604 1/20 0.46
ALDH1A1 P00352 1/20 0.46
POLB P06746 1/20 0.46
CYP3A4 P08684 1/20 0.46
MAPT P10636 1/20 0.46
HPGD P15428 1/20 0.46
ALOX15 P16050 1/20 0.46
APEX1 P27695 1/20 0.46
BLM P54132 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22717109 1.00 PTPN1 (0.71) PTPN1GPR84FFAR1FFAR4FAAH
SCHEMBL13189678 0.98 PTPN1 (0.68) PTPN1GPR84FFAR1FFAR4FAAH
SCHEMBL31672983 0.91 PTPN1 (0.65) PTPN1GPR84FFAR1FFAR4FAAH
SCHEMBL30838582 0.91 PTPN1 (0.63) PTPN1FAAHMEN1KMT2ARECQL
SCHEMBL8750020 0.91 PTPN1 (0.63) PTPN1FAAHMEN1KMT2ARECQL
SCHEMBL30838578 0.91 PTPN1 (0.63) PTPN1FAAHMEN1KMT2ARECQL
SCHEMBL31336114 0.91 PTPN1 (0.63) PTPN1FAAHMEN1KMT2ARECQL
SCHEMBL10056657 0.91 PTPN1 (0.63) PTPN1FAAHMEN1KMT2ARECQL
SCHEMBL8505361 0.91 PTPN1 (0.63) PTPN1FAAHMEN1KMT2ARECQL
SCHEMBL2810350 0.91 PTPN1 (0.63) PTPN1FAAHMEN1KMT2ARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023078273-A1 SPECIFIC CONJUGATION FOR AN ANTIBODY-DRUG CONJUGATE HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-05-11 WO disclosed
US-20120231972-A1 Probe Compound for Detecting and Isolating Enzymes and Means and Methods Using the Same INSTITUTE OF CATALYSIS (CSIC) (ES) 2012-09-13 US disclosed
WO-2010105851-A1 PROBE COMPOUND FOR DETECTING AND ISOLATING ENZYMES AND MEANS AND METHODS USING THE SAME Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2010-09-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120231972-A1 Probe Compound for Detecting and Isolating Enzymes and Means and Methods Using the Same SI, GUSB, MPI PTPN1 3648/4885GPR84 2028/4885FFAR1 3168/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.