Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 1/20 | 0.62 |
| ▸ | CDK8 | P49336 | 1/20 | 0.62 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.57 |
| ▸ | SCN10A | Q9Y5Y9 | 5/20 | 0.55 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.53 |
| ▸ | SMO | Q99835 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27828390 | 0.91 | CCNC (0.64) | CCNCCDK8PTPN1SCN10AKAT6A | |
| SCHEMBL12191060 | 0.87 | SCN10A (0.72) | CCNCCDK8PTPN1SCN10ASMO | |
| SCHEMBL27828346 | 0.87 | HTT (0.64) | CCNCCDK8PTPN1SCN10APOLB | |
| SCHEMBL485860 | 0.84 | CCNC (0.64) | CCNCCDK8PTPN1SCN10ASMO | |
| SCHEMBL14640457 | 0.84 | KCNK9 (0.59) | CCNCCDK8PTPN1SCN10APOLB | |
| SCHEMBL12191048 | 0.83 | ABL1 (0.68) | CCNCCDK8SMN1; SMN2NPC1LMNA | |
| SCHEMBL12190912 | 0.82 | CCNC (0.53) | CCNCCDK8PTPN1SCN10ANPC1 | |
| SCHEMBL12190908 | 0.81 | CCNC (0.65) | CCNCCDK8SCN10APOLBSMN1; SMN2 | |
| SCHEMBL27984049 | 0.81 | MEN1 (0.74) | CCNCCDK8DEGS1PTPN1POLB | |
| SCHEMBL23390206 | 0.80 | ABL1 (0.79) | SCN10AKCNH2ABL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030336-B2 | Nicotinamide-based kinase inhibitors | YM BIOSCIENCES AUSTRALIA PTY LTD (AU) | 2011-10-04 | — | — | US | disclosed |
| US-8030336-B2 | Nicotinamide-based kinase inhibitors | YM BIOSCIENCES AUSTRALIA PTY LTD (AU) | 2011-10-04 | — | — | US | disclosed |
| US-20070060619-A1 | Nicotinamide-based kinase inhibitors | CYTOPIA PTY LTD (AU) | 2007-03-15 | — | — | US | disclosed |
| US-20070060619-A1 | Nicotinamide-based kinase inhibitors | CYTOPIA PTY LTD (AU) | 2007-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060619-A1 | Nicotinamide-based kinase inhibitors | NADK, NAMPT, PDXK | CCNC 1755/4885CDK8 218/4885DEGS1 2831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.