Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 5/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | PNP | P00491 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | FABP6 | P51161 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24066325 | 0.78 | TSHR (0.38) | ALDH1A1DHFRSLC2A1DAOTRPV1 | |
| SCHEMBL20756712 | 0.78 | GSK3B (0.41) | MEN1ALDH1A1KMT2ADHFRSLC2A1 | |
| SCHEMBL1321755 | 0.76 | — | — | |
| SCHEMBL31231913 | 0.73 | CYP3A4 (0.57) | CYP3A4BLMMEN1ALDH1A1KMT2A | |
| SCHEMBL24500022 | 0.73 | PNP (0.43) | MEN1ALDH1A1KMT2APNPTRPV1 | |
| SCHEMBL25899174 | 0.73 | DHFR (0.38) | CYP3A4BLMMEN1ALDH1A1KMT2A | |
| SCHEMBL24538722 | 0.73 | PNP (0.38) | CYP3A4BLMMEN1ALDH1A1KMT2A | |
| SCHEMBL908315 | 0.72 | — | — | |
| SCHEMBL12192595 | 0.72 | KDM4E (0.40) | CYP3A4BLMBACE1XDHDHFR | |
| SCHEMBL32678515 | 0.71 | CYP3A4 (0.42) | CYP3A4MEN1KMT2ACYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210371403-A1 | SMALL MOLECULES TARGETING MUTANT MAMMALIAN PROTEINS | JNANA THERAPEUTICS INC. | 2021-12-02 | — | — | US | disclosed |
| WO-2020061473-A1 | SMALL MOLECULES TARGETING MUTANT MAMMALIAN PROTEINS | JNANA THERAPEUTICS, INC. (US) | 2020-03-26 | — | — | WO | disclosed |
| US-9006364-B2 | Supramolecular polymers from low-melting, easily processable building blocks | SUPRAPOLIX B.V. (NL) | 2015-04-14 | — | — | US | disclosed |
| US-9006364-B2 | Supramolecular polymers from low-melting, easily processable building blocks | SUPRAPOLIX B.V. (NL) | 2015-04-14 | — | — | US | disclosed |
| US-20140142256-A1 | SUPRAMOLECULAR POLYMERS FROM LOW-MELTING, EASILY PROCESSABLE BUILDING BLOCKS | SUPRAPOLIX B.V. (NL) | 2014-05-22 | — | — | US | disclosed |
| US-20140142256-A1 | SUPRAMOLECULAR POLYMERS FROM LOW-MELTING, EASILY PROCESSABLE BUILDING BLOCKS | SUPRAPOLIX B.V. (NL) | 2014-05-22 | — | — | US | disclosed |
| EP-2087027-B1 | SUPRAMOLECULAR POLYMERS FROM LOW-MELTING, EASILY PROCESSABLE BUILDING BLOCKS | SUPRAPOLIX BV (NL) | 2011-10-05 | — | — | EP | disclosed |
| US-20100076147-A1 | SUPRAMOLECULAR POLYMERS FROM LOW-MELTING, EASILY PROCESSABLE BUILDING BLOCKS | SUPRAPOLIX B.V. (NL) | 2010-03-25 | — | — | US | disclosed |
| US-20100076147-A1 | SUPRAMOLECULAR POLYMERS FROM LOW-MELTING, EASILY PROCESSABLE BUILDING BLOCKS | SUPRAPOLIX B.V. (NL) | 2010-03-25 | — | — | US | disclosed |
| WO-2008063057-A2 | SUPRAMOLECULAR POLYMERS FROM LOW-MELTING, EASILY PROCESSABLE BUILDING BLOCKS | SUPRAPOLIX B.V. (NL) | 2008-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210371403-A1 | SMALL MOLECULES TARGETING MUTANT MAMMALIAN PROTEINS | SNRPE, G3BP1, G3BP2 | CYP3A4 4879/4885BLM 1606/4885MEN1 2652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.