SCHEMBL12196998

SCHEMBL12196998

CC(=O)NC1C(OC2C(C)OC(CO)C(O)C2O)OC(CO)C(OC2OC(CO)C(O)C(OC3(OC=O)CC(O)C(C)C(C(O)C(O)CO)O3)C2O)C1O

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ MAG P20916 7/20 0.50
▸ SIGLEC7 Q9Y286 6/20 0.48
▸ SELE P16581 4/20 0.47
▸ SELL P14151 2/20 0.43
▸ SELP P16109 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16342337 1.00 MAG (0.50) MAGSIGLEC7SELESELLSELP
SCHEMBL16187918 1.00 MAG (0.50) MAGSIGLEC7SELESELLSELP
SCHEMBL25446563 1.00 MAG (0.50) MAGSIGLEC7SELESELLSELP
SCHEMBL16187872 1.00 MAG (0.50) MAGSIGLEC7SELESELLSELP
SCHEMBL12197077 0.95 MAG (0.48) MAGSIGLEC7SELESELLSELP
SCHEMBL4119673 0.95 MAG (0.48) MAGSIGLEC7SELESELLSELP
SCHEMBL17195861 0.95 MAG (0.48) MAGSIGLEC7SELESELLSELP
SCHEMBL15849102 0.95 MAG (0.48) MAGSIGLEC7SELESELLSELP
SCHEMBL16232780 0.95 MAG (0.48) MAGSIGLEC7SELESELLSELP
SCHEMBL16312032 0.95 MAG (0.48) MAGSIGLEC7SELESELLSELP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8765669-B2 Glycosylated GLP-1 peptide GLYTECH, INC. (JP) 2014-07-01 — — US disclosed
US-8507429-B2 Sugar chain added GLP-1 peptide GLYTECH, INC. (JP) 2013-08-13 — — US disclosed
US-20120264684-A1 Glycosylated Form of Antigenic GLP-1 Analogue GLYTECH, INC. (JP) 2012-10-18 — — US disclosed
US-20110245166-A1 SUGAR CHAIN ADDED GLP-1 PEPTIDE OTSUKA CHEMICAL HOLDINGS CO., LTD (JP) 2011-10-06 — — US disclosed
US-20110195897-A1 GLYCOSYLATED GLP-1 PEPTIDE OTSUKA CHEMICAL CO., LTD. (JP) 2011-08-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110195897-A1 GLYCOSYLATED GLP-1 PEPTIDE GLP1R, GIPR, IAPP MAG 1399/4885SIGLEC7 102/4885SELE 200/4885
US-20110245166-A1 SUGAR CHAIN ADDED GLP-1 PEPTIDE GLP1R, IAPP, GIPR MAG 1836/4885SIGLEC7 308/4885SELE 158/4885
US-20120264684-A1 Glycosylated Form of Antigenic GLP-1 Analogue GLP1R, GIPR, IAPP MAG 341/4885SIGLEC7 414/4885SELE 670/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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