SCHEMBL16187918

SCHEMBL16187918

CC(=O)NC1C(O)[C@H](O[C@@H]2OC(CO)[C@H](O)[C@H](O[C@]3(OC=O)C[C@@H](O)[C@@H](C)C([C@H](O)C(O)CO)O3)C2O)[C@H](CO)O[C@H]1OC1[C@@H](O)[C@H](O)C(CO)O[C@@H]1C

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ MAG P20916 7/20 0.50
▸ SIGLEC7 Q9Y286 6/20 0.48
▸ SELE P16581 4/20 0.47
▸ SELL P14151 2/20 0.43
▸ SELP P16109 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16342337 1.00 MAG (0.50) MAGSIGLEC7SELESELLSELP
SCHEMBL25446563 1.00 MAG (0.50) MAGSIGLEC7SELESELLSELP
SCHEMBL12196998 1.00 MAG (0.50) MAGSIGLEC7SELESELLSELP
SCHEMBL16187872 1.00 MAG (0.50) MAGSIGLEC7SELESELLSELP
SCHEMBL12197077 0.95 MAG (0.48) MAGSIGLEC7SELESELLSELP
SCHEMBL4119673 0.95 MAG (0.48) MAGSIGLEC7SELESELLSELP
SCHEMBL17195861 0.95 MAG (0.48) MAGSIGLEC7SELESELLSELP
SCHEMBL15849102 0.95 MAG (0.48) MAGSIGLEC7SELESELLSELP
SCHEMBL16232780 0.95 MAG (0.48) MAGSIGLEC7SELESELLSELP
SCHEMBL16312032 0.95 MAG (0.48) MAGSIGLEC7SELESELLSELP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9937264-B2 Glycosylated polypeptide and drug composition containing said polypeptide GLYTECH, INC. (JP) 2018-04-10 — — US disclosed
US-9802996-B2 Glycosylated polypeptide and drug composition containing said polypeptide GLYTECH, INC. (JP) 2017-10-31 — — US disclosed
US-9708413-B2 Glycosylated linker, compound containing glycosylated linker moiety and physiologically active substance moiety or salt thereof, and methods for producing said compound or salt thereof GLYTECH, INC. (JP) 2017-07-18 — — US disclosed
US-20170157260-A1 Glycosylated Polypeptide and Drug Composition Containing said Polypeptide GLYTECH, INC. (JP) 2017-06-08 — — US disclosed
US-20160368961-A1 Glycosylated Polypeptide and Drug Composition Containing said Polypeptide GLYTECH, INC. (JP) 2016-12-22 — — US disclosed
US-9441024-B2 Glycosylated polypeptide and drug composition containing said polypeptide GLYTECH, INC. (JP) 2016-09-13 — — US disclosed
US-9422357-B2 Glycosylated polypeptide and drug composition containing said polypeptide GLYTECH, INC. (JP) 2016-08-23 — — US disclosed
US-20150306235-A1 SUGAR CHAIN-ATTACHED LINKER, COMPOUND CONTAINING SUGAR CHAIN-ATTACHED LINKER AND PHYSIOLOGICALLY ACTIVE SUBSTANCE OR SALT THEREOF, AND METHOD FOR PRODUCING SAME GLYTECH INC (JP) 2015-10-29 — — US disclosed
US-20150299337-A1 GLYCOSYLATED LINKER, COMPOUND CONTAINING GLYCOSYLATED LINKER MOIETY AND PHYSIOLOGICALLY ACTIVE SUBSTANCE MOIETY OR SALT THEREOF, AND METHODS FOR PRODUCING SAID U OR SALT THEREOF GLYTECH INC (JP) 2015-10-22 — — US disclosed
US-20140369964-A1 GLYCOSYLATED POLYPEPTIDE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME GLYTECH, INC. (JP) 2014-12-18 — — US disclosed
US-20140336116-A1 Glycosylated Polypeptide and Drug Composition Containing Said Polypeptide GLYTECH, INC. (JP) 2014-11-13 — — US disclosed
US-20140315800-A1 Glycosylated Polypeptide and Drug Composition Containing Said Polypeptide GLYTECH, INC. (JP) 2014-10-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170157260-A1 Glycosylated Polypeptide and Drug Composition Containing said Polypeptide GIPR, SSTR4, SSTR3 MAG 784/4885SIGLEC7 100/4885SELE 428/4885
US-20150299337-A1 GLYCOSYLATED LINKER, COMPOUND CONTAINING GLYCOSYLATED LINKER MOIETY AND PHYSIOLOGICALLY ACTIVE SUBSTANCE MOIETY OR SALT THEREOF, AND METHODS FOR PRODUCING SAID U OR SALT THEREOF CD44, CSGALNACT1, UGGT1 MAG 644/4885SIGLEC7 8/4885SELE 148/4885
US-20140336116-A1 Glycosylated Polypeptide and Drug Composition Containing Said Polypeptide GIPR, SSTR4, SSTR5 MAG 778/4885SIGLEC7 104/4885SELE 430/4885
US-20150306235-A1 SUGAR CHAIN-ATTACHED LINKER, COMPOUND CONTAINING SUGAR CHAIN-ATTACHED LINKER AND PHYSIOLOGICALLY ACTIVE SUBSTANCE OR SALT THEREOF, AND METHOD FOR PRODUCING SAME SI, ENGASE, DNPEP MAG 1177/4885SIGLEC7 29/4885SELE 219/4885
US-20160368961-A1 Glycosylated Polypeptide and Drug Composition Containing said Polypeptide GIPR, SSTR3, SSTR4 MAG 766/4885SIGLEC7 92/4885SELE 440/4885
US-20140315800-A1 Glycosylated Polypeptide and Drug Composition Containing Said Polypeptide GIPR, SSTR3, SSTR4 MAG 766/4885SIGLEC7 92/4885SELE 440/4885
US-20140369964-A1 GLYCOSYLATED POLYPEPTIDE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME IFNG, IFNAR1, IAPP MAG 1226/4885SIGLEC7 20/4885SELE 1381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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