Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 3/20 | 0.56 |
| ▸ | CDC25B | P30305 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | LIG1 | P18858 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CDC25A | P30304 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9724319 | 0.91 | HPGD (0.59) | HSD17B10HPGDALOX15MEN1LMNA | |
| Phthalic Acid SCHEMBL8765730 | 0.87 | PARP10 (0.57) | HSD17B10HPGDALOX15MEN1LMNA | |
| SCHEMBL63564 | 0.85 | AKR1C3 (0.76) | AKR1C3CDC25BATMNR4A1LIG1 | |
| SCHEMBL29360039 | 0.85 | AKR1C3 (0.76) | AKR1C3CDC25BATMNR4A1LIG1 | |
| SCHEMBL9724321 | 0.83 | KMT2A (0.63) | HSD17B10HPGDALOX15MEN1LMNA | |
| SCHEMBL10783424 | 0.83 | HSD17B10 (0.62) | AKR1C3HSD17B10HPGDALOX15MEN1 | |
| SCHEMBL7627722 | 0.82 | HSD17B10 (0.61) | AKR1C3HSD17B10HPGDALOX15LMNA | |
| Hydroquinone SCHEMBL28293513 | 0.82 | HSD17B10 (0.71) | HSD17B10HPGDALOX15MEN1LMNA | |
| SCHEMBL11267684 | 0.80 | HPGD (0.58) | NR4A1HSD17B10HPGDALOX15MEN1 | |
| Phthalic Acid SCHEMBL9391164 | 0.80 | HSD17B10 (0.68) | AKR1C3HSD17B10HPGDALOX15LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110044938-A1 | TETRAHYDROBENZOTHIOPHENE DERIVATIVES | NYCOMED GMBH (DE) | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110044938-A1 | TETRAHYDROBENZOTHIOPHENE DERIVATIVES | BAX, BCL2, BAD | AKR1C3 2004/4885CDC25B 366/4885ATM 1184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.