Phthalic Acid

Phthalic Acid

SCHEMBL8765730

O=C(O)c1ccccc1C(=O)O.O=C(Oc1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.57

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP10 Q53GL7 1/20 0.57
ESR1 P03372 2/20 0.55
ESR2 Q92731 2/20 0.55
ALOX15 P16050 2/20 0.51
HPGD P15428 1/20 0.51
HSD17B10 Q99714 1/20 0.51
KMT2A Q03164 7/20 0.51
MEN1 O00255 3/20 0.51
MAPT P10636 4/20 0.50
ALDH1A1 P00352 4/20 0.50
TDP1 Q9NUW8 3/20 0.50
LMNA P02545 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
PKM P14618 1/20 0.50
NSD2 O96028 1/20 0.49
RAB9A P51151 1/20 0.47
PRSS1 P07477 1/20 0.47
ACR P10323 1/20 0.47
TMPRSS15 P98073 1/20 0.47
POLB P06746 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9724319 0.89 HPGD (0.59) ESR1ESR2ALOX15HPGDHSD17B10
SCHEMBL5162040 0.89 PARP10 (0.70) PARP10ESR1ESR2HSD17B10KMT2A
Phthalic Acid SCHEMBL10802155 0.89 PARP10 (0.59) PARP10ALOX15HPGDHSD17B10KMT2A
SCHEMBL1219706 0.87 AKR1C3 (0.56) ALOX15HPGDHSD17B10KMT2AMEN1
SCHEMBL455541 0.87 PARP10 (0.61) PARP10ESR1ESR2ALOX15HPGD
SCHEMBL281981 0.87 PARP10 (0.67) PARP10ESR1ESR2HSD17B10KMT2A
SCHEMBL667872 0.85 CA1 (0.64) PARP10HSD17B10KMT2AMEN1MAPT
SCHEMBL8422974 0.85 CA1 (0.64) PARP10HSD17B10KMT2AMEN1MAPT
SCHEMBL20500513 0.85 CA1 (0.64) PARP10HSD17B10KMT2AMEN1MAPT
SCHEMBL17734117 0.85 CA1 (0.64) PARP10HSD17B10KMT2AMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0427795-B1 HIGH STRENGTH POLYMER BLENDS OF HYDROQUINONE POLY(ISO-TEREPHTHALATES) CONTAINING RESIDUES OF p-HYDROXYBENZOIC ACID AMOCO CORP (US) 1997-08-13 EP disclosed
EP-0395750-B1 HEAT RESISTANT POLYMERS AND BLENDS OF HYDROQUINONE POLY(ISO-TEREPHTHALATES) CONTAINING RESIDUES OF p-HYDROXYBENZOIC ACID AMOCO CORP (US) 1997-04-02 EP disclosed
US-5296542-A Heat resistant polymers and blends of hydroquinone poly (isoterephthalates) containing residues of p-hydroxybenzoic acid AMOCO CORPORATION (US) 1994-03-22 US disclosed
US-5216091-A Molded ovenware; resists blistering bubbling and cracking during molding AMOCO CORPORATION (US) 1993-06-01 US disclosed
US-5204417-A High strength polymers and blends of hydroquinone poly(iso-terephthalates) containing residues of p-hydroxybenzoic acid AMOCO CORPORATION (US) 1993-04-20 US disclosed
EP-0427795-A4 HIGH STRENGTH POLYMERS AND BLENDS OF HYDROQUINONE POLY(ISO-TEREPHTHALATES) CONTAINING RESIDUES OF P-HYDROXYBENZOIC ACID 1992-11-25 EP disclosed
US-5147967-A Molding materials which form stable workable melts, mechanical properties AMOCO CORPORATION (US) 1992-09-15 US disclosed
US-5097001-A High modulus and high strength, preparation by reacting monomers in lower monocarboxylic acid anhydride solvent, melt processable, blend with another aromatic polyester SOLVAY ADVANCED POLYMERS, L.L.C. 1992-03-17 US disclosed
US-5079289-A Heat resistance, molding materials, ovenware, electronic equipment AMOCO CORPORATION (US) 1992-01-07 US disclosed
EP-0427795-A1 HIGH STRENGTH POLYMERS AND BLENDS OF HYDROQUINONE POLY(ISO-TEREPHTHALATES) CONTAINING RESIDUES OF p-HYDROXYBENZOIC ACID. AMOCO CORP (US) 1991-05-22 EP disclosed
WO-1990004001-A1 HEAT RESISTANT POLYMERS AND BLENDS OF HYDROQUINONE POLY(ISO-TEREPHTHALATES) CONTAINING RESIDUES OF p-HYDROXYBENZOIC ACID AMOCO CORPORATION (US) 1990-04-19 WO disclosed
WO-1990004003-A1 HIGH STRENGTH POLYMERS AND BLENDS OF HYDROQUINONE POLY(ISO-TEREPHTHALATES) CONTAINING RESIDUES OF p-HYDROXYBENZOIC ACID AMOCO CORPORATION (US) 1990-04-19 WO disclosed