Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 16/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2497101 | 0.89 | HDAC1 (0.48) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL12199650 | 0.83 | HDAC1 (0.52) | HDAC1HTTSMN1; SMN2HDAC3HDAC2 | |
| SCHEMBL12199930 | 0.83 | HDAC1 (0.52) | HDAC1HTTSMN1; SMN2HDAC3HDAC2 | |
| SCHEMBL2480604 | 0.80 | HDAC1 (0.58) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL16269680 | 0.79 | ATM (0.48) | HDAC1HTTHDAC3HDAC2HDAC8 | |
| SCHEMBL12286676 | 0.78 | ALDH1A1 (0.44) | HDAC1SMN1; SMN2HDAC3HDAC2NCOR2 | |
| SCHEMBL12199753 | 0.77 | HTT (0.47) | HDAC1HTTSMN1; SMN2HDAC3HDAC2 | |
| SCHEMBL12199815 | 0.77 | HDAC1 (0.46) | HDAC1HTTSMN1; SMN2HDAC3HDAC2 | |
| SCHEMBL2474430 | 0.76 | HDAC1 (0.51) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL2479909 | 0.76 | HDAC1 (0.48) | HDAC1HDAC3HDAC2HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2107052-B1 | NOVEL N-(2-AMINOPHENYL)BENZAMIDE DERIVATIVE HAVING AN UREA STRUCTURE | SANTEN PHARMACEUTICAL CO LTD (JP) | 2011-10-12 | — | — | EP | disclosed |