Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12199836 | 0.81 | NPC1 (0.58) | NPC1RAB9AKDM4EGAACYP2C9 | |
| SCHEMBL12199835 | 0.76 | NPC1 (0.54) | NPC1RAB9AKDM4EGAACYP2C9 | |
| SCHEMBL12199834 | 0.76 | NPC1 (0.42) | NPC1RAB9AKDM4EGAACYP2C9 | |
| SCHEMBL10873172 | 0.73 | NPC1 (0.48) | NPC1RAB9AKDM4EGAACYP2C9 | |
| SCHEMBL7149442 | 0.72 | NPC1 (0.39) | NPC1RAB9AKDM4EGAACYP2C9 | |
| SCHEMBL31155592 | 0.72 | NPC1 (0.51) | NPC1RAB9AKDM4EGAACYP2C9 | |
| SCHEMBL7149445 | 0.69 | CNR1 (0.39) | NPC1RAB9A | |
| SCHEMBL6672691 | 0.69 | NPC1 (0.48) | NPC1RAB9AKDM4ESMN1; SMN2LMNA | |
| SCHEMBL29491989 | 0.69 | NPC1 (0.58) | NPC1RAB9AKDM4EGAACYP2C9 | |
| SCHEMBL8017347 | 0.69 | NPC1 (0.58) | NPC1RAB9AKDM4EGAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8034878-B2 | Low molecular weight ethylene interpolymers, methods of making, and uses thereof | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-10-11 | — | — | US | disclosed |
| US-8034878-B2 | Low molecular weight ethylene interpolymers, methods of making, and uses thereof | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-10-11 | — | — | US | disclosed |
| US-20080306217-A1 | Low Molecular Weight Ethylene Interpolymers, Methods of Making, and Uses Thereof | DOW GLOBAL TECHNOLOGIES LLC | 2008-12-11 | — | — | US | disclosed |
| US-20080306217-A1 | Low Molecular Weight Ethylene Interpolymers, Methods of Making, and Uses Thereof | DOW GLOBAL TECHNOLOGIES LLC | 2008-12-11 | — | — | US | disclosed |
| US-7259219-B2 | Low molecular weight copolymer of ethylene and vinyl aromatic monomer and uses thereof | DOW GLOBAL TECHNOLOGIES INC. (US) | 2007-08-21 | — | — | US | disclosed |
| WO-2007078697-A1 | LOW MOLECULAR WEIGHT ETHYLENE INTERPOLYMERS, METHODS OF MAKING, AND USES THEREOF | DOW GLOBAL TECHNOLOGIES INC. (US) | 2007-07-12 | — | — | WO | disclosed |