Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | USP7 | Q93009 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28325434 | 0.81 | NPC1 (0.43) | NPC1RAB9APTPN1LMNAPOLB | |
| SCHEMBL22363749 | 0.80 | HDAC4 (0.47) | NPC1RAB9ALMNAPOLBHPGD | |
| SCHEMBL9408808 | 0.79 | NPC1 (0.43) | NPC1RAB9APTPN1LMNAPOLB | |
| SCHEMBL27553358 | 0.78 | KDM4E (0.44) | NPC1RAB9ALMNAHPGDKDM4E | |
| SCHEMBL1703200 | 0.77 | LMNA (0.63) | NPC1RAB9ALMNAPOLBHPGD | |
| SCHEMBL20591061 | 0.77 | FFAR1 (0.43) | NPC1RAB9APTPN1POLB | |
| SCHEMBL29595889 | 0.76 | PTPN1 (0.64) | PTPN1HPGDBACE1CRHBPCRHR2 | |
| SCHEMBL4979055 | 0.75 | NPC1 (0.43) | NPC1RAB9APTPN1LMNAPOLB | |
| SCHEMBL11408951 | 0.75 | NPC1 (0.43) | NPC1RAB9ALMNAPOLBHPGD | |
| SCHEMBL309670 | 0.74 | PTPN1 (0.67) | PTPN1HPGDBACE1CRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0992363-B1 | Heat-sensitive recording material | FUJI PHOTO FILM CO LTD (JP) | 2004-09-22 | — | — | EP | disclosed |
| EP-0992363-A1 | Heat-sensitive recording material | FUJI PHOTO FILM CO., LTD. (JP) | 2000-04-12 | — | — | EP | disclosed |
| US-4663642-A | DISCOLORATION INHIBITION | RICOH COMPANY, LTD. (JP) | 1987-05-05 | — | — | US | disclosed |