SCHEMBL12200525

SCHEMBL12200525

CCC(C)C(=O)CCCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.37

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.37
USP2 O75604 1/20 0.33
MAPT P10636 1/20 0.33
TSHR P16473 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12200526 1.00 CES2 (0.37) CES2USP2MAPTTSHRGAA
SCHEMBL14282536 0.79 GAA (0.35) USP2MAPTTSHRGAA
SCHEMBL2759376 0.79 GAA (0.35) USP2MAPTTSHRGAA
SCHEMBL2759380 0.77 GAA (0.34) USP2MAPTTSHRGAA
SCHEMBL2759377 0.77 GAA (0.34) USP2MAPTTSHRGAA
SCHEMBL2759374 0.75 GAA (0.35) USP2MAPTTSHRGAA
SCHEMBL13475913 0.75 TSHR (0.36) USP2MAPTTSHRGAA
SCHEMBL12938888 0.75 TSHR (0.36) USP2MAPTTSHRGAA
SCHEMBL2759372 0.75 GAA (0.35) USP2MAPTTSHRGAA
SCHEMBL18412470 0.74 TSHR (0.35) USP2MAPTTSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110242654-A1 Hardcoat layer-forming composition, optical film, production method of optical film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2011-10-06 US disclosed