Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 16/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5635249 | 0.94 | CETP (0.43) | CETP | |
| SCHEMBL12201507 | 0.86 | HTR2C (0.37) | HTR2CHTR2AHTR2BCYP3A4 | |
| SCHEMBL2474951 | 0.81 | GPBAR1 (0.39) | HTR2CHTR2AHTR2BCYP3A4 | |
| SCHEMBL12200355 | 0.81 | MEN1 (0.40) | CETP | |
| SCHEMBL2475748 | 0.78 | HTR2C (0.46) | HTR2CHTR2AHTR2BCYP3A4 | |
| SCHEMBL1380240 | 0.76 | CETP (0.44) | CETP | |
| SCHEMBL1382424 | 0.76 | CETP (0.61) | CETP | |
| SCHEMBL2474218 | 0.76 | CETP (0.61) | CETP | |
| SCHEMBL3535032 | 0.76 | CETP (0.54) | CETP | |
| SCHEMBL3537448 | 0.76 | CETP (0.54) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761522-B1 | COMPOUNDS AND METHODS FOR TREATING DYSLIPIDEMIA | LILLY CO ELI (US) | 2011-10-12 | — | — | EP | disclosed |