Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 1/20 | 0.35 |
| ▸ | SFRP1 | Q8N474 | 7/20 | 0.34 |
| ▸ | WNT3 | P56703 | 3/20 | 0.34 |
| ▸ | CETP | P11597 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2494468 | 0.93 | TACR1 (0.43) | TACR1CETP | |
| SCHEMBL2494470 | 0.93 | TACR1 (0.43) | TACR1CETP | |
| SCHEMBL2481314 | 0.82 | CETP (0.39) | TACR1CETP | |
| SCHEMBL12200547 | 0.81 | HTR2C (0.36) | CETP | |
| SCHEMBL2475991 | 0.81 | CETP (0.54) | CETP | |
| SCHEMBL12200987 | 0.81 | CETP (0.47) | CETP | |
| SCHEMBL2475998 | 0.81 | CETP (0.54) | CETP | |
| SCHEMBL12201557 | 0.80 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL2127581 | 0.79 | CETP (0.47) | TACR1CETP | |
| SCHEMBL3537504 | 0.79 | CETP (0.47) | TACR1CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761522-B1 | COMPOUNDS AND METHODS FOR TREATING DYSLIPIDEMIA | LILLY CO ELI (US) | 2011-10-12 | — | — | EP | disclosed |