SCHEMBL12201237

SCHEMBL12201237

CCCCC/C=C\C/C=C\CCCCCCCCNC(=O)CCC(C)(C)C

nearest known ligand 0.74

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 6/20 0.69
KDM4E B2RXH2 1/20 0.65
ALDH1A1 P00352 2/20 0.64
HPGD P15428 2/20 0.64
TRPV1 Q8NER1 1/20 0.64
MEN1 O00255 1/20 0.64
MAPT P10636 1/20 0.64
ALOX12 P18054 1/20 0.64
BLM P54132 1/20 0.64
KMT2A Q03164 1/20 0.64
TDP1 Q9NUW8 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12201222 0.96 EPHX2 (0.67) CNR1KDM4E
SCHEMBL8704897 0.88 CNR1 (0.82) CNR1KDM4EALDH1A1HPGDTRPV1
SCHEMBL24134447 0.87 CNR1 (0.76) CNR1ALDH1A1HPGDTRPV1MEN1
SCHEMBL8541979 0.87 EPHX2 (0.72) CNR1KDM4EALDH1A1HPGDTRPV1
SCHEMBL8541977 0.87 EPHX2 (0.72) CNR1KDM4EALDH1A1HPGDTRPV1
SCHEMBL9964253 0.87 CNR1 (0.85) CNR1KDM4EALDH1A1HPGDTRPV1
SCHEMBL15456964 0.87 CNR1 (0.79) CNR1KDM4EALDH1A1HPGDTRPV1
SCHEMBL14849281 0.87 CNR1 (0.85) CNR1KDM4EALDH1A1HPGDTRPV1
SCHEMBL6286194 0.87 CNR1 (0.85) CNR1KDM4EALDH1A1HPGDTRPV1
SCHEMBL6286826 0.87 CNR1 (0.85) CNR1KDM4EALDH1A1HPGDTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230174459-A1 LIPID CONTAINING FORMULATIONS ARBUTUS BIOPHARMA CORPORATION (US) 2023-06-08 US disclosed
US-20200361854-A1 LIPID CONTAINING FORMULATIONS ARBUTUS BIOPHARMA CORPORATION (CA) 2020-11-19 US disclosed
US-20180065918-A1 LIPID CONTAINING FORMULATIONS ARBUTUS BIOPHARMA CORPORATION (CA) 2018-03-08 US disclosed
US-9663449-B2 2017-05-30 US disclosed
US-8034376-B2 Lipid containing formulations Alnylam Pharamaceticals, Inc. (US) 2011-10-11 US disclosed
US-20090023673-A1 LIPID CONTAINING FORMULATIONS BANK OF AMERICA, N.A. 2009-01-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200361854-A1 LIPID CONTAINING FORMULATIONS LIPA, POLRMT, PHOSPHO1 CNR1 4299/4885KDM4E 3221/4885ALDH1A1 3971/4885
US-20180065918-A1 LIPID CONTAINING FORMULATIONS LIPA, POLRMT, PHOSPHO1 CNR1 4299/4885KDM4E 3221/4885ALDH1A1 3971/4885
US-20230174459-A1 LIPID CONTAINING FORMULATIONS LIPA, POLRMT, PHOSPHO1 CNR1 4299/4885KDM4E 3221/4885ALDH1A1 3971/4885
US-20090023673-A1 LIPID CONTAINING FORMULATIONS LIPA, POLRMT, PHOSPHO1 CNR1 4299/4885KDM4E 3221/4885ALDH1A1 3971/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.